| geneid | 80332 |
|---|---|
| ensemblid | ENSG00000149451.19 |
| hgncid | 15478 |
| symbol | ADAM33 |
| name | ADAM metallopeptidase domain 33 |
| refseq_nuc | NM_025220.5 |
| refseq_prot | NP_079496.1 |
| ensembl_nuc | ENST00000356518.7 |
| ensembl_prot | ENSP00000348912.3 |
| mane_status | MANE Select |
| chr | chr20 |
| start | 3667975 |
| end | 3682010 |
| strand | - |
| ver | v1.2 |
| region | chr20:3667975-3682010 |
| region5000 | chr20:3662975-3687010 |
| regionname0 | ADAM33_chr20_3667975_3682010 |
| regionname5000 | ADAM33_chr20_3662975_3687010 |
| chr:pos | ref | alt | af | annotation | impact | samples | AHAPIDS | ACHAPIDS | ACTHAPIDS | ACTGHAPIDS | ac | an | len | genename | geneid | featuretype | featureid | transcript_biotype | rank | hgvs_c | hgvs_p | cdna_pos_length | cds_pos_length | aa_pos_length | distance | status |
|---|
| genename | grch38/chm13v2 1/0: The haplotype type is the same as GRCh380/1: The haplotype type is the same as CHM13v20/0: The haplotype type matches neither GRCh38 nor CHM13v21/1: The haplotype type is the same on both GRCh38 and CHM13v2
|
ahapid | alen | total | AFR | AMR | EAS | EUR | SAS | aseq | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAM33 | 1/1 | a0001 | 813 | 293 | 38 | 57 | 158 | 9 | 29 | subcellular location copy fasta | chr20 | 3662975 | 3687010 |
Click to load Haplotype QTL data...
| pos | S. Strand |
E# Exon Number |
max | median | min | diff | type | haplotypeid | max_hap_list | min_hap_list | symbol | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3681908 | - | 1 | -0.8702 | -0.8473 | -0.8252 | 0.0450 | acceptor | a0001 | HG02165.hp1 | NA18951.hp2 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3679492 | - | 2 | -0.9498 | -0.9346 | -0.9198 | 0.0300 | acceptor | a0001 | HG01243.hp2 | NA21309.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3679571 | - | 2 | 0.8530 | 0.8202 | 0.7873 | 0.0657 | donor | a0001 | HG00639.hp1 | NA21309.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3677067 | - | 3 | -0.9932 | -0.9926 | -0.9883 | 0.0049 | acceptor | a0001 | HG02965.hp2 | homoSapiens_chm13v2.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3677143 | - | 3 | 0.9954 | 0.9946 | 0.9913 | 0.0041 | donor | a0001 | HG02976.hp1 | HG00280.hp2 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3675027 | - | 4 | -0.9663 | -0.9481 | -0.9390 | 0.0273 | acceptor | a0001 | NA18955.hp1 | NA18957.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3675105 | - | 4 | 0.9822 | 0.9545 | 0.9509 | 0.0313 | donor | a0001 | NA18955.hp1 | NA19057.hp2 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3674773 | - | 5 | -0.9138 | -0.8654 | -0.8238 | 0.0900 | acceptor | a0001 | NA18982.hp2 NA18983.hp2 |
NA18957.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3674849 | - | 5 | 0.8925 | 0.8530 | 0.8303 | 0.0622 | donor | a0001 | NA18982.hp2 NA18983.hp2 |
NA19057.hp2 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3674504 | - | 6 | -0.7572 | -0.6668 | -0.3552 | 0.4020 | acceptor | a0001 | HG03486.hp2 | NA18957.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3674693 | - | 6 | 0.9617 | 0.9432 | 0.9352 | 0.0264 | donor | a0001 | NA18957.hp1 | HG02965.hp2 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3674219 | - | 7 | -0.9939 | -0.9905 | -0.9550 | 0.0388 | acceptor | a0001 | HG02965.hp2 | NA18957.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3674284 | - | 7 | 0.9975 | 0.9958 | 0.0006 | 0.9969 | donor | a0001 | HG02572.hp1 HG03486.hp2 |
NA18957.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3674064 | - | 8 | -0.9787 | -0.9779 | -0.9749 | 0.0038 | acceptor | a0001 | HG02257.hp2 HG02615.hp1 |
NA18957.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3674135 | - | 8 | 0.9878 | 0.9864 | 0.9843 | 0.0036 | donor | a0001 | HG02976.hp1 | NA18957.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3673745 | - | 9 | -0.8145 | -0.7865 | -0.0006 | 0.8139 | acceptor | a0001 | HG03491.hp2 | NA19007.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3673911 | - | 9 | 0.9274 | 0.9176 | 0.8831 | 0.0442 | donor | a0001 | HG02630.hp2 | NA19007.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3673574 | - | 10 | -0.9033 | -0.8792 | -0.8748 | 0.0285 | acceptor | a0001 | HG00558.hp1 | HG02572.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3673658 | - | 10 | 0.5927 | 0.5856 | 0.3833 | 0.2094 | donor | a0001 | HG00558.hp1 | NA19007.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3673354 | - | 11 | -0.9871 | -0.9860 | -0.9853 | 0.0018 | acceptor | a0001 | HG03491.hp2 | NA18957.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3673496 | - | 11 | 0.9856 | 0.9836 | 0.9804 | 0.0052 | donor | a0001 | HG00558.hp1 | NA19007.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3672721 | - | 12 | -0.9687 | -0.9666 | -0.9646 | 0.0041 | acceptor | a0001 | HG02965.hp2 | HG02486.hp2 HG02559.hp2 HG03516.hp1 NA21309.hp1 |
ADAM33 | chr20 | 3662975 | 3687010 |
| 3672898 | - | 12 | 0.8898 | 0.8691 | 0.8556 | 0.0342 | donor | a0001 | HG02976.hp1 | HG02486.hp2 HG02559.hp2 HG03516.hp1 NA21309.hp1 |
ADAM33 | chr20 | 3662975 | 3687010 |
| 3672537 | - | 13 | -0.9838 | -0.9804 | -0.9797 | 0.0040 | acceptor | a0001 | HG02976.hp1 | NA19043.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3672626 | - | 13 | 0.9683 | 0.9605 | 0.9597 | 0.0086 | donor | a0001 | HG02965.hp2 | NA19007.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3672134 | - | 14 | -0.9455 | -0.9321 | -0.9216 | 0.0239 | acceptor | a0001 | HG01884.hp2 HG02258.hp2 HG02622.hp1 HG02809.hp2 HG02886.hp1 others(2): Show |
NA19043.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3672329 | - | 14 | 0.8039 | 0.7700 | 0.7659 | 0.0380 | donor | a0001 | HG02976.hp1 | NA19007.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3671877 | - | 15 | -0.9560 | -0.9549 | -0.9306 | 0.0254 | acceptor | a0001 | HG00673.hp1 | HG02965.hp2 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3671985 | - | 15 | 0.8014 | 0.7973 | 0.7261 | 0.0753 | donor | a0001 | HG02630.hp2 | HG02965.hp2 NA19043.hp1 |
ADAM33 | chr20 | 3662975 | 3687010 |
| 3671581 | - | 16 | -0.9982 | -0.9982 | -0.9973 | 0.0009 | acceptor | a0001 | HG00673.hp1 | HG02976.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3671779 | - | 16 | 0.9984 | 0.9984 | 0.9981 | 0.0003 | donor | a0001 | HG03486.hp2 | HG02630.hp2 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3671419 | - | 17 | -0.8703 | -0.8671 | -0.8501 | 0.0203 | acceptor | a0001 | HG00673.hp1 | HG02486.hp2 HG02559.hp2 HG03516.hp1 |
ADAM33 | chr20 | 3662975 | 3687010 |
| 3671496 | - | 17 | 0.9085 | 0.9067 | 0.8593 | 0.0492 | donor | a0001 | HG03486.hp2 | HG02257.hp2 HG02615.hp1 |
ADAM33 | chr20 | 3662975 | 3687010 |
| 3671237 | - | 18 | -0.9931 | -0.9922 | -0.9907 | 0.0024 | acceptor | a0001 | HG02572.hp1 | HG02027.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3671345 | - | 18 | 0.9955 | 0.9953 | 0.9949 | 0.0006 | donor | a0001 | HG00408.hp2 HG00673.hp1 HG01978.hp2 NA18940.hp1 |
HG02257.hp2 HG02615.hp1 |
ADAM33 | chr20 | 3662975 | 3687010 |
| 3671006 | - | 19 | -0.8041 | -0.7716 | -0.7255 | 0.0786 | acceptor | a0001 | HG02818.hp2 | NA18964.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3671153 | - | 19 | 0.9509 | 0.9261 | 0.9121 | 0.0388 | donor | a0001 | HG02257.hp2 HG02615.hp1 |
HG00544.hp2 NA18963.hp1 |
ADAM33 | chr20 | 3662975 | 3687010 |
| 3669546 | - | 20 | -0.8080 | -0.7910 | -0.7777 | 0.0303 | acceptor | a0001 | NA18612.hp2 | HG02074.hp1 HG02165.hp2 NA18985.hp1 |
ADAM33 | chr20 | 3662975 | 3687010 |
| 3669637 | - | 20 | 0.5156 | 0.4977 | 0.4500 | 0.0657 | donor | a0001 | HG03225.hp2 | HG01978.hp2 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3669299 | - | 21 | -0.9493 | -0.9254 | -0.9094 | 0.0399 | acceptor | a0001 | NA18964.hp1 | NA18941.hp1 NA18999.hp1 |
ADAM33 | chr20 | 3662975 | 3687010 |
| 3669370 | - | 21 | 0.9269 | 0.9078 | 0.8929 | 0.0339 | donor | a0001 | HG00544.hp1 | HG02976.hp1 | ADAM33 | chr20 | 3662975 | 3687010 |
| 3669000 | - | 22 | 0.4248 | 0.3971 | 0.2797 | 0.1451 | donor | a0001 | HG00609.hp2 | HG02071.hp2 | ADAM33 | chr20 | 3662975 | 3687010 |
| pos | annotationhgvs_chgvs_p | clinvarid | clnsig | geneinfo | mc | clndisdb | strand strand
|
ahapid ahapid_count
|
chapid chapid count
|
thapid thapid_count
|
ghapid ghapid_count
|
AHAPIDS ahapids
|
ACHAPIDS achapids
|
ACTHAPIDS acthapids
|
ACTGHAPIDS actghapids
|
haplotypeids haplotypeids
|
impact | chr | ref | alt | external |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 3672331:splice 3672331:variant goto | c.1402-7_1402-3delTGCGC | 769073 | Benign | ADAM33:80332 | SO:0001627 intron_variant |
MedGen:C3661900 | - | 3 | 4 | 5 | 17 | a0001a0009a0017 | a0001c0006a0001c0023a0009c0016a0017c0028 | a0001c0006t0005a0001c0006t0006a0001c0023t0005a0009c0016t0004a0017c0028t0005 | a0001c0006t0005g0273a0001c0006t0005g0372a0001c0006t0006g0041a0001c0006t0006g0044a0001c0006t0006g0046others(12): Show | HG01109.hp1 HG01884.hp2 HG02258.hp2 HG02486.hp2 HG02559.hp2 others(13): Show |
LOW | chr20 | TGCGCA | T | TogoVar |
| 3672234:splice 3672234:variant goto | c.1497T>Ap.Val499Val | 769072 | Benign | ADAM33:80332 | SO:0001819 synonymous_variant |
MedGen:C3661900 | - | 2 | 3 | 3 | 3 | a0001a0013 | a0001c0027a0001c0033a0013c0040 | a0001c0027t0006a0001c0033t0003a0013c0040t0006 | a0001c0027t0006g0216a0001c0033t0003g0115a0013c0040t0006g0120 | HG01884.hp1 HG02965.hp2 NA19043.hp1 |
LOW | chr20 | A | T | TogoVar |
| CHR:POS | annotationhgvs_chgvs_p | disease trait-log10podds or beta | AHAPIDS ahapids
|
ACHAPIDS achapids
|
ACTHAPIDS acthapids
|
ACTGHAPIDS actghapids
|
haplotypeids haplotypeids
|
study | initial sample size/replication sample size | report genes | mapped gene | strongest snp risk allele | strand strand
|
impact | chr | ref | alt |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
chr20:3681495
|
c.97+413G>A | Lung function (FEV1/FVC) | a0000a0001a0002a0003a0004others(12): Show | a0000c0003a0000c0009a0000c0010a0000c0013a0000c0024others(31): Show | a0000c0003t0007a0000c0003t0008a0000c0009t0007a0000c0010t0008a0000c0013t0012others(60): Show | a0000c0003t0007g0058a0000c0003t0007g0095a0000c0003t0007g0096a0000c0003t0007g0097a0000c0003t0007g0140others(237): Show | HG00099.hp2 HG00140.hp1 HG00323.hp2 HG00408.hp1 HG00408.hp2 others(295): Show |
Leveraging Polygenic Functional Enrichment to Impr others(15): Show |
approximately 370,000 European ancestry individual others(2): Show |
ADAM33 | rs554743-? | - | MODIFIER | chr20 | C | T | |
|
chr20:3670579
|
c.2240+427C>A | COVID-19 (hospitalized vs tested, not hospitalized)others(18): Show | a0001a0002a0003a0004a0006others(9): Show | a0001c0001a0001c0012a0001c0015a0001c0025a0001c0027others(19): Show | a0001c0001t0001a0001c0001t0002a0001c0001t0003a0001c0001t0004a0001c0001t0011others(38): Show | a0001c0001t0001g0001a0001c0001t0001g0002a0001c0001t0001g0003a0001c0001t0001g0006a0001c0001t0001g0008others(176): Show | HG00099.hp2 HG00140.hp1 HG00280.hp1 HG00280.hp2 HG00323.hp1 others(237): Show |
A year of COVID-19 GWAS results from the GRASP por others(43): Show |
1,703 European ancestry male cases, 43,659 Europea others(25): Show |
ADAM33 | rs44707-T | - | MODIFIER | chr20 | G | T | |
|
chr20:3670579
|
c.2240+427C>A | COVID-19 (hospitalized vs tested, not hospitalized)others(18): Show | a0001a0002a0003a0004a0006others(9): Show | a0001c0001a0001c0012a0001c0015a0001c0025a0001c0027others(19): Show | a0001c0001t0001a0001c0001t0002a0001c0001t0003a0001c0001t0004a0001c0001t0011others(38): Show | a0001c0001t0001g0001a0001c0001t0001g0002a0001c0001t0001g0003a0001c0001t0001g0006a0001c0001t0001g0008others(176): Show | HG00099.hp2 HG00140.hp1 HG00280.hp1 HG00280.hp2 HG00323.hp1 others(237): Show |
A year of COVID-19 GWAS results from the GRASP por others(43): Show |
1,703 European ancestry male cases, 43,659 Europea others(144): Show |
ADAM33 | rs44707-T | - | MODIFIER | chr20 | G | T | |
|
chr20:3670518
|
c.2240+488C>T |
COVID-19 (hospitalized vs population)0.1 others(4): Show |
a0001a0003a0006a0007a0010others(1): Show | a0001c0001a0001c0015a0001c0025a0001c0030a0003c0005others(5): Show | a0001c0001t0001a0001c0001t0002a0001c0001t0003a0001c0001t0004a0001c0001t0011others(15): Show | a0001c0001t0001g0001a0001c0001t0001g0002a0001c0001t0001g0003a0001c0001t0001g0006a0001c0001t0001g0008others(109): Show | HG00099.hp2 HG00140.hp1 HG00280.hp1 HG00280.hp2 HG00323.hp1 others(162): Show |
A year of COVID-19 GWAS results from the GRASP por others(43): Show |
1,703 European ancestry male cases, 208,248 Europe others(146): Show |
ADAM33 | rs597980-A | - | MODIFIER | chr20 | G | A | |
|
chr20:3670518
|
c.2240+488C>T |
COVID-19 death (death vs population)0.20 others(3): Show |
a0001a0003a0006a0007a0010others(1): Show | a0001c0001a0001c0015a0001c0025a0001c0030a0003c0005others(5): Show | a0001c0001t0001a0001c0001t0002a0001c0001t0003a0001c0001t0004a0001c0001t0011others(15): Show | a0001c0001t0001g0001a0001c0001t0001g0002a0001c0001t0001g0003a0001c0001t0001g0006a0001c0001t0001g0008others(109): Show | HG00099.hp2 HG00140.hp1 HG00280.hp1 HG00280.hp2 HG00323.hp1 others(162): Show |
A year of COVID-19 GWAS results from the GRASP por others(43): Show |
1,001 European ancestry cases, 458,249 European an others(44): Show |
ADAM33 | rs597980-A | - | MODIFIER | chr20 | G | A | |
|
chr20:3670518
|
c.2240+488C>T |
COVID-19 death (death vs tested and survived) others(12): Show |
a0001a0003a0006a0007a0010others(1): Show | a0001c0001a0001c0015a0001c0025a0001c0030a0003c0005others(5): Show | a0001c0001t0001a0001c0001t0002a0001c0001t0003a0001c0001t0004a0001c0001t0011others(15): Show | a0001c0001t0001g0001a0001c0001t0001g0002a0001c0001t0001g0003a0001c0001t0001g0006a0001c0001t0001g0008others(109): Show | HG00099.hp2 HG00140.hp1 HG00280.hp1 HG00280.hp2 HG00323.hp1 others(162): Show |
A year of COVID-19 GWAS results from the GRASP por others(43): Show |
1,001 European ancestry cases, 79,558 European anc others(42): Show |
ADAM33 | rs597980-A | - | MODIFIER | chr20 | G | A | |
|
chr20:3680142
|
c.98-571A>G | Chronic obstructive pulmonary disease liability (machine learning-based score)others(45): Show | a0000a0001a0002a0003a0004others(12): Show | a0000c0003a0000c0009a0000c0010a0000c0013a0000c0029others(35): Show | a0000c0003t0007a0000c0003t0008a0000c0003t0032a0000c0009t0007a0000c0010t0008others(74): Show | a0000c0003t0007g0058a0000c0003t0007g0095a0000c0003t0007g0096a0000c0003t0007g0097a0000c0003t0007g0140others(282): Show | HG00099.hp2 HG00140.hp1 HG00280.hp2 HG00323.hp1 HG00323.hp2 others(342): Show |
Inference of chronic obstructive pulmonary disease others(91): Show |
325,027 European ancestry individuals/ | ADAM33 | rs603112-T | - | MODIFIER | chr20 | T | C | |
|
chr20:3681495
|
c.97+413G>A | White blood cell count0.014312 | a0000a0001a0002a0003a0004others(12): Show | a0000c0003a0000c0009a0000c0010a0000c0013a0000c0024others(31): Show | a0000c0003t0007a0000c0003t0008a0000c0009t0007a0000c0010t0008a0000c0013t0012others(60): Show | a0000c0003t0007g0058a0000c0003t0007g0095a0000c0003t0007g0096a0000c0003t0007g0097a0000c0003t0007g0140others(237): Show | HG00099.hp2 HG00140.hp1 HG00323.hp2 HG00408.hp1 HG00408.hp2 others(295): Show |
Trans-ethnic and Ancestry-Specific Blood-Cell Gene others(54): Show |
562,243 European ancestry individuals/ | NR | ADAM33 | rs554743-T | - | MODIFIER | chr20 | C | T |
|
chr20:3681495
|
c.97+413G>A | White blood cell count | a0000a0001a0002a0003a0004others(12): Show | a0000c0003a0000c0009a0000c0010a0000c0013a0000c0024others(31): Show | a0000c0003t0007a0000c0003t0008a0000c0009t0007a0000c0010t0008a0000c0013t0012others(60): Show | a0000c0003t0007g0058a0000c0003t0007g0095a0000c0003t0007g0096a0000c0003t0007g0097a0000c0003t0007g0140others(237): Show | HG00099.hp2 HG00140.hp1 HG00323.hp2 HG00408.hp1 HG00408.hp2 others(295): Show |
Trans-ethnic and Ancestry-Specific Blood-Cell Gene others(54): Show |
746,667 African American or Afro-Caribbean, Africa others(116): Show |
NR | ADAM33 | rs554743-T | - | MODIFIER | chr20 | C | T |
|
chr20:3686434
|
c.-4430G>A | Human papillomavirus seropositivity (HPV16 E6/E7/L1 or HPV18 L1)others(31): Show | a0001a0002a0003 | a0001c0001a0002c0002a0003c0005 | a0001c0001t0001a0002c0002t0002a0002c0002t0004a0003c0005t0001a0003c0005t0004 | a0001c0001t0001g0185a0002c0002t0002g0131a0002c0002t0004g0130a0003c0005t0001g0157a0003c0005t0004g0009others(1): Show | HG01069.hp1 HG01071.hp1 HG01516.hp1 HG01517.hp2 HG02698.hp2 others(4): Show |
Genome-Wide Association Analyses of HPV16 and HPV1 others(66): Show |
784 European ancestry cases, 7,140 European ancest others(12): Show |
ADAM33 - SIGLEC1 | rs6084436-T | - | MODIFIER | chr20 | C | T | |
|
chr20:3681593
|
c.97+315C>T | Human papillomavirus seropositivity (HPV16 E6/E7/L1)others(19): Show | a0000a0001a0002a0003a0004others(3): Show | a0000c0003a0000c0029a0001c0001a0001c0006a0001c0015others(7): Show | a0000c0003t0007a0000c0029t0022a0001c0001t0001a0001c0001t0002a0001c0001t0003others(19): Show | a0000c0003t0007g0140a0000c0029t0022g0147a0001c0001t0001g0026a0001c0001t0001g0138a0001c0001t0001g0150others(65): Show | HG00408.hp2 HG00423.hp1 HG00423.hp2 HG00438.hp2 HG00558.hp2 others(77): Show |
Genome-Wide Association Analyses of HPV16 and HPV1 others(66): Show |
674 European ancestry cases, 7,140 European ancest others(12): Show |
ADAM33 | rs78389827-A | - | MODIFIER | chr20 | G | A | |
|
chr20:3681495
|
c.97+413G>A | Lung function (FEV1/FVC)6.733 | a0000a0001a0002a0003a0004others(12): Show | a0000c0003a0000c0009a0000c0010a0000c0013a0000c0024others(31): Show | a0000c0003t0007a0000c0003t0008a0000c0009t0007a0000c0010t0008a0000c0013t0012others(60): Show | a0000c0003t0007g0058a0000c0003t0007g0095a0000c0003t0007g0096a0000c0003t0007g0097a0000c0003t0007g0140others(237): Show | HG00099.hp2 HG00140.hp1 HG00323.hp2 HG00408.hp1 HG00408.hp2 others(295): Show |
Multi-ancestry genome-wide association analyses im others(112): Show |
475,645 European ancestry individuals, 8,590 Afric others(151): Show |
ADAM33 | rs554743-T | - | MODIFIER | chr20 | C | T | |
|
chr20:3663006
|
c.*5957C>T | Height0.0044 | a0001a0002a0004a0006a0008others(4): Show | a0001c0001a0002c0002a0002c0008a0002c0018a0004c0004others(6): Show | a0001c0001t0002a0001c0001t0003a0001c0001t0004a0001c0001t0006a0001c0001t0010others(21): Show | a0001c0001t0002g0004a0001c0001t0002g0056a0001c0001t0002g0070a0001c0001t0002g0079a0001c0001t0002g0151others(83): Show | HG00140.hp2 HG00323.hp2 HG00408.hp2 HG00544.hp1 HG00673.hp2 others(97): Show |
A saturated map of common genetic variants associa others(22): Show |
5,314,291 European ancestry, Hispanic or Latin Ame others(79): Show |
GFRA4 | rs6084432-A | - | MODIFIER | chr20 | G | A | |
|
chr20:3681495
|
c.97+413G>A | Reticulocyte count0.016524322 | a0000a0001a0002a0003a0004others(12): Show | a0000c0003a0000c0009a0000c0010a0000c0013a0000c0024others(31): Show | a0000c0003t0007a0000c0003t0008a0000c0009t0007a0000c0010t0008a0000c0013t0012others(60): Show | a0000c0003t0007g0058a0000c0003t0007g0095a0000c0003t0007g0096a0000c0003t0007g0097a0000c0003t0007g0140others(237): Show | HG00099.hp2 HG00140.hp1 HG00323.hp2 HG00408.hp1 HG00408.hp2 others(295): Show |
The Polygenic and Monogenic Basis of Blood Traits others(13): Show |
408,112 British individuals/ | ADAM33 | ADAM33 | rs554743-T | - | MODIFIER | chr20 | C | T |
|
chr20:3670579
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c.2240+427C>A | White blood cell count0.0137116825 | a0001a0002a0003a0004a0006others(9): Show | a0001c0001a0001c0012a0001c0015a0001c0025a0001c0027others(19): Show | a0001c0001t0001a0001c0001t0002a0001c0001t0003a0001c0001t0004a0001c0001t0011others(38): Show | a0001c0001t0001g0001a0001c0001t0001g0002a0001c0001t0001g0003a0001c0001t0001g0006a0001c0001t0001g0008others(176): Show | HG00099.hp2 HG00140.hp1 HG00280.hp1 HG00280.hp2 HG00323.hp1 others(237): Show |
The Polygenic and Monogenic Basis of Blood Traits others(13): Show |
408,112 British individuals/ | ADAM33 | ADAM33 | rs44707-T | - | MODIFIER | chr20 | G | T |
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chr20:3684158
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c.-2154A>G | Platelet distribution width0.021203341 | a0000a0001a0002a0003a0004others(12): Show | a0000c0003a0000c0009a0000c0010a0000c0013a0000c0024others(33): Show | a0000c0003t0007a0000c0003t0008a0000c0003t0032a0000c0009t0007a0000c0010t0008others(73): Show | a0000c0003t0007g0058a0000c0003t0007g0095a0000c0003t0007g0096a0000c0003t0007g0097a0000c0003t0007g0140others(290): Show | HG00099.hp2 HG00140.hp1 HG00280.hp1 HG00280.hp2 HG00323.hp2 others(350): Show |
The Polygenic and Monogenic Basis of Blood Traits others(13): Show |
408,112 British individuals/ | ADAM33 | ADAM33 - SIGLEC1 | rs601081-C | - | MODIFIER | chr20 | T | C |