| geneid | 8751 |
|---|---|
| ensemblid | ENSG00000143537.14 |
| hgncid | 193 |
| symbol | ADAM15 |
| name | ADAM metallopeptidase domain 15 |
| refseq_nuc | NM_207197.3 |
| refseq_prot | NP_997080.1 |
| ensembl_nuc | ENST00000356955.7 |
| ensembl_prot | ENSP00000349436.2 |
| mane_status | MANE Select |
| chr | chr1 |
| start | 155051316 |
| end | 155062775 |
| strand | + |
| ver | v1.2 |
| region | chr1:155051316-155062775 |
| region5000 | chr1:155046316-155067775 |
| regionname0 | ADAM15_chr1_155051316_155062775 |
| regionname5000 | ADAM15_chr1_155046316_155067775 |
| chr:pos | ref | alt | af | annotation | impact | samples | AHAPIDS | ACHAPIDS | ACTHAPIDS | ACTGHAPIDS | ac | an | len | genename | geneid | featuretype | featureid | transcript_biotype | rank | hgvs_c | hgvs_p | cdna_pos_length | cds_pos_length | aa_pos_length | distance | status |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
chr1:155054466
|
A | C | 0.9167 | missense_variant | MODERATE | HG00099.hp1 HG00099.hp2 HG00140.hp1 others(294): Show |
a0001a0002a0004others(6): Show | a0001c0001a0001c0002a0001c0004others(14): Show | a0001c0001t0001a0001c0001t0003a0001c0002t0001others(16): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004others(106): Show | 297 | 324 | 0 | ADAM15 | ENSG00000143537.14 | transcript | ENST00000356955.7 | protein_coding | 6/23 | c.572A>C | p.Lys191Thr | 643/2936 | 572/2592 | 191/863 |
| chr:pos | ref | alt | af | annotation | impact | samples | ahapids | achapids | acthapids | actghapids | ac | an | len | genename | geneid | featuretype | featureid | transcript_biotype | rank | hgvs_c | hgvs_p | cdna_pos_length | cds_pos_length | aa_pos_length | distance | status |
|---|
| chr:pos | ref | alt | af | annotation | impact | samples | ahapids | achapids | acthapids | actghapids | ac | an | len | genename | geneid | featuretype | featureid | transcript_biotype | rank | hgvs_c | hgvs_p | cdna_pos_length | cds_pos_length | aa_pos_length | distance | status |
|---|
| genename | grch38/chm13v2 1/0: The haplotype type is the same as GRCh380/1: The haplotype type is the same as CHM13v20/0: The haplotype type matches neither GRCh38 nor CHM13v21/1: The haplotype type is the same on both GRCh38 and CHM13v2
|
ahapid | alen | total | AFR | AMR | EAS | EUR | SAS | aseq | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAM15 | 0/1 | a0001 | 863 | 234 | 50 | 46 | 88 | 11 | 38 | subcellular location copy fasta | chr1 | 155046316 | 155067775 |
| genename | grch38/chm13v2 1/0: The haplotype type is the same as GRCh380/1: The haplotype type is the same as CHM13v20/0: The haplotype type matches neither GRCh38 nor CHM13v21/1: The haplotype type is the same on both GRCh38 and CHM13v2
|
chapid | clen | total | AFR | AMR | EAS | EUR | SAS | cseq | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAM15 | 0/0 | c0001 | 2592 | 160 | 21 | 27 | 84 | 7 | 21 | copy fasta | chr1 | 155046316 | 155067775 |
| genename | grch38/chm13v2 | thapid | tlen | total | AFR | AMR | EAS | EUR | SAS | tseq | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAM15 | 1/1 | t0001 | 345 | 319 | 92 | 63 | 98 | 16 | 48 | copy fasta | chr1 | 155046316 | 155067775 |
| genename | grch38/chm13v2 1/0: The haplotype type is the same as GRCh380/1: The haplotype type is the same as CHM13v20/0: The haplotype type matches neither GRCh38 nor CHM13v21/1: The haplotype type is the same on both GRCh38 and CHM13v2 |
achapid | total | AFR | AMR | EAS | EUR | SAS | clen | cseq | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAM15 | 0/0 | a0001c0001 | 160 | 21 | 27 | 84 | 7 | 21 | 2592 | copy fasta | chr1 | 155046316 | 155067775 |
| genename | grch38/chm13v2 1/0: The haplotype type is the same as GRCh380/1: The haplotype type is the same as CHM13v20/0: The haplotype type matches neither GRCh38 nor CHM13v21/1: The haplotype type is the same on both GRCh38 and CHM13v2 |
acthapid | total | AFR | AMR | EAS | EUR | SAS | tlen | tseq | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAM15 | 0/0 | a0001c0001t0001 | 159 | 21 | 26 | 84 | 7 | 21 | 2936 | copy fasta | chr1 | 155046316 | 155067775 |
Click to load Haplotype QTL data...
| pos | S. Strand |
E# Exon Number |
max | median | min | diff | type | haplotypeid | max_hap_list | min_hap_list | symbol | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 155051465 | + | 1 | -0.9812 | -0.9750 | -0.9728 | 0.0084 | acceptor | a0001c0001t0001 | HG01070.hp1 | HG02015.hp2 HG02083.hp2 |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155052671 | + | 2 | 0.8442 | 0.8036 | 0.7987 | 0.0455 | donor | a0001c0001t0001 | HG03831.hp1 NA20905.hp1 |
HG01070.hp1 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155052777 | + | 2 | -0.9468 | -0.9305 | -0.9180 | 0.0288 | acceptor | a0001c0001t0001 | HG03098.hp2 | HG03704.hp2 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155053417 | + | 3 | 0.6693 | 0.6601 | 0.6089 | 0.0604 | donor | a0001c0001t0001 | HG01496.hp2 | HG03704.hp2 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155053493 | + | 3 | -0.6803 | -0.6414 | -0.5992 | 0.0812 | acceptor | a0001c0001t0001 | HG03831.hp1 NA20905.hp1 |
HG03471.hp1 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155053910 | + | 4 | 0.9932 | 0.9930 | 0.9924 | 0.0008 | donor | a0001c0001t0001 | HG03516.hp2 | HG03704.hp2 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155053988 | + | 4 | -0.9973 | -0.9968 | -0.9968 | 0.0005 | acceptor | a0001c0001t0001 | HG03831.hp1 NA20905.hp1 |
HG00423.hp2 HG00544.hp1 HG00597.hp1 HG01070.hp1 HG01123.hp2 others(10): Show |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155054150 | + | 5 | 0.5113 | 0.5003 | 0.4911 | 0.0202 | donor | a0001c0001t0001 | HG01891.hp2 HG02145.hp1 NA18906.hp1 |
HG03041.hp1 HG03486.hp1 HG03579.hp2 NA18522.hp2 |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155054226 | + | 5 | -0.7465 | -0.7389 | -0.7374 | 0.0091 | acceptor | a0001c0001t0001 | HG03471.hp1 | HG04228.hp1 NA18944.hp1 NA18970.hp2 NA18998.hp2 NA19010.hp1 others(1): Show |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155054314 | + | 6 | 0.9939 | 0.9935 | 0.9934 | 0.0005 | donor | a0001c0001t0001 | HG03098.hp2 | HG03041.hp1 HG03486.hp1 HG03579.hp2 NA18522.hp2 |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155054506 | + | 6 | -0.9948 | -0.9947 | -0.9946 | 0.0003 | acceptor | a0001c0001t0001 | NA19067.hp2 NA19090.hp2 |
HG03704.hp2 HG03831.hp1 NA20905.hp1 |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155055790 | + | 7 | 0.8971 | 0.8962 | 0.8925 | 0.0045 | donor | a0001c0001t0001 | HG00639.hp2 HG00735.hp1 NA19030.hp1 NA21309.hp2 |
HG03471.hp1 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155055852 | + | 7 | -0.9018 | -0.9015 | -0.8987 | 0.0031 | acceptor | a0001c0001t0001 | HG00423.hp2 HG00544.hp1 HG00597.hp1 HG00673.hp2 HG01123.hp2 others(6): Show |
HG03041.hp1 HG03486.hp1 HG03579.hp2 NA18522.hp2 |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155055932 | + | 8 | 0.9967 | 0.9967 | 0.9963 | 0.0004 | donor | a0001c0001t0001 | NA19067.hp2 NA19090.hp2 |
HG03471.hp1 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155056000 | + | 8 | -0.9956 | -0.9953 | -0.9944 | 0.0012 | acceptor | a0001c0001t0001 | HG03041.hp1 HG03486.hp1 HG03579.hp2 NA18522.hp2 |
HG03098.hp2 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155056080 | + | 9 | 0.7104 | 0.6983 | 0.6376 | 0.0729 | donor | a0001c0001t0001 | HG03041.hp1 HG03486.hp1 HG03579.hp2 NA18522.hp2 |
HG03098.hp2 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155056249 | + | 9 | -0.6799 | -0.6631 | -0.6626 | 0.0173 | acceptor | a0001c0001t0001 | HG03471.hp1 | HG04228.hp1 NA18944.hp1 NA18970.hp2 NA18998.hp2 NA19010.hp1 others(1): Show |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155056386 | + | 10 | 0.9840 | 0.9830 | 0.9809 | 0.0031 | donor | a0001c0001t0001 | NA19067.hp2 NA19090.hp2 |
HG03098.hp2 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155056470 | + | 10 | -0.9958 | -0.9945 | -0.9944 | 0.0014 | acceptor | a0001c0001t0001 | HG03098.hp2 | HG03041.hp1 HG03486.hp1 HG03579.hp2 NA18522.hp2 |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155056953 | + | 11 | 0.9967 | 0.9965 | 0.9965 | 0.0002 | donor | a0001c0001t0001 | HG03098.hp2 | HG03041.hp1 HG03486.hp1 HG03579.hp2 NA18522.hp2 |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155057101 | + | 11 | -0.9982 | -0.9981 | -0.9981 | 0.0001 | acceptor | a0001c0001t0001 | HG00423.hp2 HG00544.hp1 HG00597.hp1 HG00673.hp2 HG00735.hp1 others(25): Show |
HG00140.hp1 HG00280.hp1 HG00323.hp2 HG00408.hp1 HG00408.hp2 others(103): Show |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155057188 | + | 12 | 0.9987 | 0.9987 | 0.9987 | 0.0000 | donor | a0001c0001t0001 | HG03098.hp2 NA18981.hp1 NA18986.hp1 |
HG00639.hp2 HG01106.hp1 HG01123.hp2 HG01517.hp1 HG02602.hp2 others(9): Show |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155057362 | + | 12 | -0.9958 | -0.9957 | -0.9957 | 0.0001 | acceptor | a0001c0001t0001 | HG02080.hp1 | HG03041.hp1 HG03486.hp1 HG03579.hp2 NA18522.hp2 |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155057637 | + | 13 | 0.9938 | 0.9936 | 0.9934 | 0.0004 | donor | a0001c0001t0001 | HG02080.hp1 | HG03834.hp1 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155057729 | + | 13 | -0.9944 | -0.9943 | -0.9940 | 0.0005 | acceptor | a0001c0001t0001 | NA18981.hp1 NA18986.hp1 |
HG02080.hp1 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155057851 | + | 14 | 0.9634 | 0.9630 | 0.9626 | 0.0008 | donor | a0001c0001t0001 | NA18981.hp1 NA18986.hp1 |
HG02080.hp1 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155058155 | + | 14 | -0.9868 | -0.9867 | -0.9863 | 0.0005 | acceptor | a0001c0001t0001 | HG00438.hp1 NA19007.hp1 |
HG00639.hp2 HG01106.hp1 HG01123.hp2 HG01517.hp1 HG02602.hp2 others(3): Show |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155058246 | + | 15 | 0.9966 | 0.9965 | 0.9965 | 0.0001 | donor | a0001c0001t0001 | HG02080.hp1 | HG00639.hp2 HG01106.hp1 HG01123.hp2 HG01517.hp1 HG02602.hp2 others(4): Show |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155058441 | + | 15 | -0.9742 | -0.9741 | -0.9731 | 0.0011 | acceptor | a0001c0001t0001 | HG00438.hp1 NA19007.hp1 |
HG00639.hp2 HG01106.hp1 HG01123.hp2 HG01517.hp1 HG02602.hp2 others(3): Show |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155058710 | + | 16 | 0.9751 | 0.9748 | 0.9741 | 0.0010 | donor | a0001c0001t0001 | HG00438.hp1 NA19007.hp1 |
HG01070.hp1 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155058787 | + | 16 | -0.9857 | -0.9856 | -0.9843 | 0.0015 | acceptor | a0001c0001t0001 | NA19009.hp1 | HG00639.hp2 HG01106.hp1 HG01123.hp2 HG01517.hp1 HG02602.hp2 others(3): Show |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155059902 | + | 17 | 0.9962 | 0.9960 | 0.9959 | 0.0003 | donor | a0001c0001t0001 | NA18981.hp1 NA18986.hp1 |
HG01070.hp1 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155059974 | + | 17 | -0.9845 | -0.9834 | -0.9829 | 0.0016 | acceptor | a0001c0001t0001 | NA18981.hp1 NA18986.hp1 |
HG03098.hp1 HG03486.hp2 |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155060205 | + | 18 | 0.9891 | 0.9884 | 0.9882 | 0.0009 | donor | a0001c0001t0001 | NA18981.hp1 NA18986.hp1 |
HG03098.hp2 HG03471.hp1 NA18977.hp2 |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155060343 | + | 18 | -0.9936 | -0.9933 | -0.9932 | 0.0004 | acceptor | a0001c0001t0001 | HG00735.hp1 HG02602.hp1 HG02615.hp2 HG02818.hp1 HG04228.hp2 others(4): Show |
HG03098.hp2 HG03471.hp1 |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155060763 | + | 19 | 0.9837 | 0.9805 | 0.9777 | 0.0060 | donor | a0001c0001t0001 | HG00438.hp1 NA19007.hp1 |
HG00639.hp2 HG01106.hp1 HG01123.hp2 HG01517.hp1 HG02602.hp2 others(3): Show |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155060832 | + | 19 | -0.9892 | -0.9858 | -0.9825 | 0.0067 | acceptor | a0001c0001t0001 | HG00438.hp1 NA19007.hp1 |
HG03098.hp2 HG03471.hp1 |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155061415 | + | 20 | 0.9259 | 0.9033 | 0.8772 | 0.0486 | donor | a0001c0001t0001 | HG01891.hp2 HG02145.hp1 HG03516.hp2 NA18906.hp1 |
HG02698.hp2 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155061489 | + | 20 | -0.8755 | -0.8613 | -0.8512 | 0.0243 | acceptor | a0001c0001t0001 | HG01891.hp2 HG02145.hp1 HG03516.hp2 NA18906.hp1 |
HG06807.hp1 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155061904 | + | 21 | 0.9729 | 0.9712 | 0.9710 | 0.0019 | donor | a0001c0001t0001 | HG06807.hp1 | NA18995.hp2 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155061975 | + | 21 | -0.9574 | -0.9538 | -0.9532 | 0.0041 | acceptor | a0001c0001t0001 | HG06807.hp1 | HG01975.hp1 | ADAM15 | chr1 | 155046316 | 155067775 |
| 155062245 | + | 22 | 0.9621 | 0.9609 | 0.9581 | 0.0039 | donor | a0001c0001t0001 | HG00438.hp1 NA19007.hp1 |
HG03491.hp2 HG03492.hp2 |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155062369 | + | 22 | -0.9420 | -0.9418 | -0.9397 | 0.0023 | acceptor | a0001c0001t0001 | HG00438.hp1 NA19007.hp1 |
HG00639.hp2 HG01106.hp1 HG01123.hp2 HG01517.hp1 HG02602.hp2 others(1): Show |
ADAM15 | chr1 | 155046316 | 155067775 |
| 155062460 | + | 23 | 0.9659 | 0.9640 | 0.9635 | 0.0025 | donor | a0001c0001t0001 | HG06807.hp1 | HG01975.hp1 | ADAM15 | chr1 | 155046316 | 155067775 |
| pos | annotationhgvs_chgvs_p | clinvarid | clnsig | geneinfo | mc | clndisdb | strand strand
|
ahapid ahapid_count
|
chapid chapid count
|
thapid thapid_count
|
ghapid ghapid_count
|
AHAPIDS ahapids
|
ACHAPIDS achapids
|
ACTHAPIDS acthapids
|
ACTGHAPIDS actghapids
|
haplotypeids haplotypeids
|
impact | chr | ref | alt | external |
|---|
| CHR:POS | annotationhgvs_chgvs_p | disease trait-log10podds or beta | AHAPIDS ahapids
|
ACHAPIDS achapids
|
ACTHAPIDS acthapids
|
ACTGHAPIDS actghapids
|
haplotypeids haplotypeids
|
study | initial sample size/replication sample size | report genes | mapped gene | strongest snp risk allele | strand strand
|
impact | chr | ref | alt |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
chr1:155054466
|
c.572A>Cp.Lys191Thr | Calcium levels0.0255 | a0001a0002a0004a0005a0006others(4): Show | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0012others(12): Show | a0001c0001t0001a0001c0001t0003a0001c0002t0001a0001c0002t0002a0001c0004t0001others(14): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0008a0001c0001t0001g0012others(104): Show | HG00099.hp1 HG00099.hp2 HG00140.hp1 HG00140.hp2 HG00280.hp1 others(292): Show |
Genetics of 35 blood and urine biomarkers in the U others(10): Show |
313,387 European ancestry individuals, 5,576 Afric others(64): Show |
NR | ADAM15 | rs6427128-C | + | MODERATE | chr1 | A | C |
|
chr1:155052885
|
c.186+108T>C | Gamma glutamyl transferase levels0.0322 | a0001a0002a0005a0009 | a0001c0001a0001c0012a0001c0015a0001c0018a0002c0009others(2): Show | a0001c0001t0001a0001c0001t0003a0001c0012t0001a0001c0015t0001a0001c0018t0001others(3): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0012a0001c0001t0001g0015others(25): Show | HG00140.hp1 HG00280.hp1 HG00323.hp2 HG00408.hp1 HG00408.hp2 others(121): Show |
Genetics of 35 blood and urine biomarkers in the U others(10): Show |
342,339 European ancestry individuals, 6,015 Afric others(64): Show |
NR | ADAM15 | rs2306125-C | + | MODIFIER | chr1 | T | C |
|
chr1:155052831
|
c.186+54A>G | Facial morphology (segment 41) | a0001 | a0001c0001 | a0001c0001t0001 | a0001c0001t0001g0048a0001c0001t0001g0049 | HG03098.hp2 HG03471.hp1 |
Genome scans of facial features in East Africans a others(58): Show |
2,595 Tanzanian ancestry individuals/ | ADAM15 | rs58409393-? | + | MODIFIER | chr1 | A | G | |
|
chr1:155056046
|
c.745-34G>A | Walking pace0.00705795 | a0001a0002a0011 | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0013others(2): Show | a0001c0001t0001a0001c0002t0001a0001c0002t0002a0001c0004t0001a0001c0010t0001others(3): Show | a0001c0001t0001g0048a0001c0001t0001g0049a0001c0002t0001g0002a0001c0002t0001g0006a0001c0002t0001g0010others(39): Show | HG00099.hp1 HG00099.hp2 HG00140.hp2 HG00323.hp1 HG00639.hp1 others(96): Show |
Genome-wide association study of self-reported wal others(78): Show |
450,967 European ancestry individuals/ | ADAM15 | ADAM15 | rs11264302-G | + | MODIFIER | chr1 | G | A |
|
chr1:155054466
|
c.572A>Cp.Lys191Thr | Serum albumin levels0.0385 | a0001a0002a0004a0005a0006others(4): Show | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0012others(12): Show | a0001c0001t0001a0001c0001t0003a0001c0002t0001a0001c0002t0002a0001c0004t0001others(14): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0008a0001c0001t0001g0012others(104): Show | HG00099.hp1 HG00099.hp2 HG00140.hp1 HG00140.hp2 HG00280.hp1 others(292): Show |
Genetics of 35 blood and urine biomarkers in the U others(10): Show |
313,032 European ancestry individuals, 5,573 Afric others(64): Show |
NR | ADAM15 | rs6427128-C | + | MODERATE | chr1 | A | C |
|
chr1:155054466
|
c.572A>Cp.Lys191Thr | Urea levels0.0411 | a0001a0002a0004a0005a0006others(4): Show | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0012others(12): Show | a0001c0001t0001a0001c0001t0003a0001c0002t0001a0001c0002t0002a0001c0004t0001others(14): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0008a0001c0001t0001g0012others(104): Show | HG00099.hp1 HG00099.hp2 HG00140.hp1 HG00140.hp2 HG00280.hp1 others(292): Show |
Genetics of 35 blood and urine biomarkers in the U others(10): Show |
342,286 European ancestry individuals, 6,015 Afric others(64): Show |
NR | ADAM15 | rs6427128-C | + | MODERATE | chr1 | A | C |
|
chr1:155052885
|
c.186+108T>C | Urate levels0.025 | a0001a0002a0005a0009 | a0001c0001a0001c0012a0001c0015a0001c0018a0002c0009others(2): Show | a0001c0001t0001a0001c0001t0003a0001c0012t0001a0001c0015t0001a0001c0018t0001others(3): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0012a0001c0001t0001g0015others(25): Show | HG00140.hp1 HG00280.hp1 HG00323.hp2 HG00408.hp1 HG00408.hp2 others(121): Show |
Genetics of 35 blood and urine biomarkers in the U others(10): Show |
342,087 European ancestry individuals, 6,011 Afric others(64): Show |
NR | ADAM15 | rs2306125-C | + | MODIFIER | chr1 | T | C |
|
chr1:155051158
|
c.-229G>A | Atrial fibrillation (MTAG)0.011636195 | a0001a0002a0005a0006a0008others(2): Show | a0001c0001a0001c0012a0001c0015a0001c0018a0002c0009others(5): Show | a0001c0001t0001a0001c0001t0003a0001c0012t0001a0001c0015t0001a0001c0018t0001others(6): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0015a0001c0001t0001g0018others(32): Show | HG00140.hp1 HG00280.hp1 HG00323.hp2 HG00408.hp1 HG00408.hp2 others(129): Show |
Multi-trait association analysis reveals shared ge others(65): Show |
at least 60,620 European ancestry cases, at least others(90): Show |
DCST1-AS1, ADAM15 | rs78266397-A | + | MODIFIER | chr1 | G | A | |
|
chr1:155056777
|
c.1000-176A>C | Disintegrin and metalloproteinase domain-containing protein 15:Extracellular domain levelsothers(56): Show | a0001 | a0001c0001 | a0001c0001t0001 | a0001c0001t0001g0008a0001c0001t0001g0012a0001c0001t0001g0022a0001c0001t0001g0028a0001c0001t0001g0029others(13): Show | HG00423.hp2 HG00544.hp1 HG00597.hp1 HG00639.hp2 HG00673.hp2 others(35): Show |
Proteogenomic analysis of human cerebrospinal flui others(103): Show |
2,721 European ancestry individuals/ | ADAM15 | rs3765087-C | + | MODIFIER | chr1 | A | C | |
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chr1:155061096
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c.2277+264A>G | COVID-19 hospitalization or systemic lupus erythematosus (MTAG)others(23): Show | a0001a0002a0003a0004a0005others(6): Show | a0001c0001a0001c0002a0001c0004a0001c0013a0001c0015others(12): Show | a0001c0001t0001a0001c0001t0003a0001c0002t0001a0001c0002t0002a0001c0004t0001others(14): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0008a0001c0001t0001g0012others(88): Show | HG00099.hp1 HG00140.hp1 HG00140.hp2 HG00280.hp1 HG00280.hp2 others(262): Show |
Disentangling the common genetic architecture and others(173): Show |
32,519 European ancestry COVID-19 hospitalization others(79): Show |
ADAM15 | rs11264305-? | + | MODIFIER | chr1 | A | G | |
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chr1:155061096
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c.2277+264A>G | COVID-19 infection or systemic lupus erythematosus (MTAG)others(17): Show | a0001a0002a0003a0004a0005others(6): Show | a0001c0001a0001c0002a0001c0004a0001c0013a0001c0015others(12): Show | a0001c0001t0001a0001c0001t0003a0001c0002t0001a0001c0002t0002a0001c0004t0001others(14): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0008a0001c0001t0001g0012others(88): Show | HG00099.hp1 HG00140.hp1 HG00140.hp2 HG00280.hp1 HG00280.hp2 others(262): Show |
Disentangling the common genetic architecture and others(173): Show |
122,616 European ancestry COVID-19 infection cases others(74): Show |
ADAM15 | rs11264305-? | + | MODIFIER | chr1 | A | G | |
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chr1:155055287
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c.613-503A>G | Extrapulmonary tuberculosis4.076 | a0001a0002a0011 | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0013others(2): Show | a0001c0001t0001a0001c0002t0001a0001c0002t0002a0001c0004t0001a0001c0010t0001others(3): Show | a0001c0001t0001g0048a0001c0001t0001g0049a0001c0002t0001g0002a0001c0002t0001g0006a0001c0002t0001g0010others(39): Show | HG00099.hp1 HG00099.hp2 HG00140.hp2 HG00323.hp1 HG00639.hp1 others(96): Show |
Genome-wide association study of tuberculosis in t others(46): Show |
330 Chinese Han ancestry cases, 1,584 Chinese Han others(18): Show |
ADAM15 | rs10158328-G | + | MODIFIER | chr1 | A | G | |
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chr1:155060841
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c.2277+9T>C | Blood pressure (pleiotropy model 1 DBP adjusted for estimated causal effects x SBP)others(43): Show | a0001a0002a0003a0005a0007others(2): Show | a0001c0001a0001c0002a0001c0004a0001c0015a0001c0018others(7): Show | a0001c0001t0001a0001c0001t0003a0001c0002t0001a0001c0004t0001a0001c0015t0001others(8): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0012a0001c0001t0001g0015others(66): Show | HG00099.hp1 HG00140.hp1 HG00140.hp2 HG00280.hp1 HG00280.hp2 others(214): Show |
Genome-wide pleiotropy analysis identifies novel b others(62): Show |
757,601 European ancestry individuals, 318,891 Eur others(105): Show |
ADAM15 | rs11264304-? | + | MODIFIER | chr1 | T | C | |
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chr1:155047234
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c.-4153A>C | Parkinson disease0.836 | a0001a0002a0003a0004a0005others(1): Show | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0012others(9): Show | a0001c0001t0001a0001c0001t0003a0001c0002t0001a0001c0002t0002a0001c0004t0001others(11): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0008a0001c0001t0001g0012others(58): Show | HG00099.hp2 HG00140.hp1 HG00280.hp1 HG00280.hp2 HG00323.hp1 others(199): Show |
A genome-wide association study coupled with machi others(110): Show |
6,868 cases, 204 controls/ | DCST1-AS1, DCST1 | rs11264300-? | + | MODIFIER | chr1 | A | C | |
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chr1:155060858
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c.2277+26G>A | Triglyceride levels | a0001 | a0001c0001a0001c0002a0001c0004 | a0001c0001t0001a0001c0002t0001a0001c0004t0001 | a0001c0001t0001g0022a0001c0001t0001g0029a0001c0001t0001g0030a0001c0001t0001g0038a0001c0001t0001g0046others(10): Show | HG00099.hp2 HG00639.hp1 HG00639.hp2 HG00735.hp1 HG00738.hp1 others(24): Show |
The power of genetic diversity in genome-wide asso others(26): Show |
40,963 South Asian ancestry individuals, 48,057 Hi others(157): Show |
ADAM15 | rs12743272-? | + | MODIFIER | chr1 | G | A | |
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chr1:155056046
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c.745-34G>A | Orbital telorism0.1074 | a0001a0002a0011 | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0013others(2): Show | a0001c0001t0001a0001c0002t0001a0001c0002t0002a0001c0004t0001a0001c0010t0001others(3): Show | a0001c0001t0001g0048a0001c0001t0001g0049a0001c0002t0001g0002a0001c0002t0001g0006a0001c0002t0001g0010others(39): Show | HG00099.hp1 HG00099.hp2 HG00140.hp2 HG00323.hp1 HG00639.hp1 others(96): Show |
Genetic architecture of orbital telorism. | 34,130 European ancestry individuals/ | ADAM15 | rs11264302-? | + | MODIFIER | chr1 | G | A | |
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chr1:155052885
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c.186+108T>C | Height0.0096 | a0001a0002a0005a0009 | a0001c0001a0001c0012a0001c0015a0001c0018a0002c0009others(2): Show | a0001c0001t0001a0001c0001t0003a0001c0012t0001a0001c0015t0001a0001c0018t0001others(3): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0012a0001c0001t0001g0015others(25): Show | HG00140.hp1 HG00280.hp1 HG00323.hp2 HG00408.hp1 HG00408.hp2 others(121): Show |
A saturated map of common genetic variants associa others(22): Show |
5,314,291 European ancestry, Hispanic or Latin Ame others(79): Show |
ADAM15 | rs2306125-C | + | MODIFIER | chr1 | T | C | |
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chr1:155053638
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c.263+145C>T |
hemoglobin (mean, inv-norm transformed)0 others(6): Show |
a0001a0002a0003a0004a0007others(1): Show | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0013others(7): Show | a0001c0001t0001a0001c0002t0001a0001c0002t0002a0001c0004t0001a0001c0010t0001others(8): Show | a0001c0001t0001g0048a0001c0001t0001g0049a0001c0002t0001g0002a0001c0002t0001g0006a0001c0002t0001g0010others(55): Show | HG00099.hp1 HG00099.hp2 HG00140.hp2 HG00280.hp2 HG00323.hp1 others(136): Show |
Diversity and scale: Genetic architecture of 2068 others(41): Show |
114,985 African American or Afro-Caribbean individ others(130): Show |
ADAM15 | rs6660884-C | + | MODIFIER | chr1 | C | T | |
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chr1:155053638
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c.263+145C>T | red blood cell count (RBC, mean, inv-norm transformed)others(21): Show | a0001a0002a0003a0004a0007others(1): Show | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0013others(7): Show | a0001c0001t0001a0001c0002t0001a0001c0002t0002a0001c0004t0001a0001c0010t0001others(8): Show | a0001c0001t0001g0048a0001c0001t0001g0049a0001c0002t0001g0002a0001c0002t0001g0006a0001c0002t0001g0010others(55): Show | HG00099.hp1 HG00099.hp2 HG00140.hp2 HG00280.hp2 HG00323.hp1 others(136): Show |
Diversity and scale: Genetic architecture of 2068 others(41): Show |
405,366 European ancestry individuals/ | ADAM15 | rs6660884-C | + | MODIFIER | chr1 | C | T | |
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chr1:155053638
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c.263+145C>T | red blood cell count (RBC, minimum, inv-norm transformed)others(24): Show | a0001a0002a0003a0004a0007others(1): Show | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0013others(7): Show | a0001c0001t0001a0001c0002t0001a0001c0002t0002a0001c0004t0001a0001c0010t0001others(8): Show | a0001c0001t0001g0048a0001c0001t0001g0049a0001c0002t0001g0002a0001c0002t0001g0006a0001c0002t0001g0010others(55): Show | HG00099.hp1 HG00099.hp2 HG00140.hp2 HG00280.hp2 HG00323.hp1 others(136): Show |
Diversity and scale: Genetic architecture of 2068 others(41): Show |
405,369 European ancestry individuals/ | ADAM15 | rs6660884-C | + | MODIFIER | chr1 | C | T | |
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chr1:155054466
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c.572A>Cp.Lys191Thr |
Bicarbonate (maximum, inv-norm transformed) others(10): Show |
a0001a0002a0004a0005a0006others(4): Show | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0012others(12): Show | a0001c0001t0001a0001c0001t0003a0001c0002t0001a0001c0002t0002a0001c0004t0001others(14): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0008a0001c0001t0001g0012others(104): Show | HG00099.hp1 HG00099.hp2 HG00140.hp1 HG00140.hp2 HG00280.hp1 others(292): Show |
Diversity and scale: Genetic architecture of 2068 others(41): Show |
412,277 European ancestry individuals/ | ADAM15 | rs6427128-A | + | MODERATE | chr1 | A | C | |
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chr1:155052885
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c.186+108T>C | Intestinal gastric cancer in H. pylori positive individualsothers(23): Show | a0001a0002a0005a0009 | a0001c0001a0001c0012a0001c0015a0001c0018a0002c0009others(2): Show | a0001c0001t0001a0001c0001t0003a0001c0012t0001a0001c0015t0001a0001c0018t0001others(3): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0012a0001c0001t0001g0015others(25): Show | HG00140.hp1 HG00280.hp1 HG00323.hp2 HG00408.hp1 HG00408.hp2 others(121): Show |
rs2671655 single nucleotide polymorphism modulates others(131): Show |
578 East Asian ancestry individuals/ | ADAM15 | rs2306125-T | + | MODIFIER | chr1 | T | C | |
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chr1:155054466
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c.572A>Cp.Lys191Thr |
Bicarbonate (maximum, inv-norm transformed) others(10): Show |
a0001a0002a0004a0005a0006others(4): Show | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0012others(12): Show | a0001c0001t0001a0001c0001t0003a0001c0002t0001a0001c0002t0002a0001c0004t0001others(14): Show | a0001c0001t0001g0001a0001c0001t0001g0003a0001c0001t0001g0004a0001c0001t0001g0008a0001c0001t0001g0012others(104): Show | HG00099.hp1 HG00099.hp2 HG00140.hp1 HG00140.hp2 HG00280.hp1 others(292): Show |
Diversity and scale: Genetic architecture of 2068 others(41): Show |
112,830 African American or Afro-Caribbean individ others(130): Show |
ADAM15 | rs6427128-A | + | MODERATE | chr1 | A | C | |
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chr1:155053638
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c.263+145C>T | hematocrit (minimum, inv-norm transformed)others(9): Show | a0001a0002a0003a0004a0007others(1): Show | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0013others(7): Show | a0001c0001t0001a0001c0002t0001a0001c0002t0002a0001c0004t0001a0001c0010t0001others(8): Show | a0001c0001t0001g0048a0001c0001t0001g0049a0001c0002t0001g0002a0001c0002t0001g0006a0001c0002t0001g0010others(55): Show | HG00099.hp1 HG00099.hp2 HG00140.hp2 HG00280.hp2 HG00323.hp1 others(136): Show |
Diversity and scale: Genetic architecture of 2068 others(41): Show |
407,854 European ancestry individuals/ | ADAM15 | rs6660884-C | + | MODIFIER | chr1 | C | T | |
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chr1:155053638
|
c.263+145C>T |
hematocrit (mean, inv-norm transformed)0 others(6): Show |
a0001a0002a0003a0004a0007others(1): Show | a0001c0001a0001c0002a0001c0004a0001c0010a0001c0013others(7): Show | a0001c0001t0001a0001c0002t0001a0001c0002t0002a0001c0004t0001a0001c0010t0001others(8): Show | a0001c0001t0001g0048a0001c0001t0001g0049a0001c0002t0001g0002a0001c0002t0001g0006a0001c0002t0001g0010others(55): Show | HG00099.hp1 HG00099.hp2 HG00140.hp2 HG00280.hp2 HG00323.hp1 others(136): Show |
Diversity and scale: Genetic architecture of 2068 others(41): Show |
407,852 European ancestry individuals/ | ADAM15 | rs6660884-C | + | MODIFIER | chr1 | C | T |