| geneid | 140766 |
|---|---|
| ensemblid | ENSG00000138316.11 |
| hgncid | 14899 |
| symbol | ADAMTS14 |
| name | ADAM metallopeptidase with thrombospondin type 1 motif 14 |
| refseq_nuc | NM_080722.4 |
| refseq_prot | NP_542453.2 |
| ensembl_nuc | ENST00000373207.2 |
| ensembl_prot | ENSP00000362303.1 |
| mane_status | MANE Select |
| chr | chr10 |
| start | 70672506 |
| end | 70762441 |
| strand | + |
| ver | v1.2 |
| region | chr10:70672506-70762441 |
| region5000 | chr10:70667506-70767441 |
| regionname0 | ADAMTS14_chr10_70672506_70762441 |
| regionname5000 | ADAMTS14_chr10_70667506_70767441 |
| chr:pos | ref | alt | af | annotation | impact | samples | AHAPIDS | ACHAPIDS | ACTHAPIDS | ACTGHAPIDS | ac | an | len | genename | geneid | featuretype | featureid | transcript_biotype | rank | hgvs_c | hgvs_p | cdna_pos_length | cds_pos_length | aa_pos_length | distance | status |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
chr10:70741007
|
T | C | 0.8136 | missense_variant | MODERATE | HG00099.hp1 HG00099.hp2 HG00140.hp1 others(285): Show |
a0001a0002a0004others(20): Show | a0001c0002a0001c0004a0001c0005others(68): Show | a0001c0002t0002a0001c0002t0007a0001c0002t0013others(119): Show | a0001c0002t0002g0110a0001c0002t0002g0113a0001c0002t0002g0116others(284): Show | 288 | 354 | 0 | ADAMTS14 | ENSG00000138316.11 | transcript | ENST00000373207.2 | protein_coding | 12/22 | c.1769T>C | p.Leu590Pro | 2066/5557 | 1769/3672 | 590/1223 | ||
|
chr10:70758074
|
G | A | 0.2599 | missense_variant | MODERATE | HG00099.hp2 HG00280.hp1 HG00408.hp2 others(89): Show |
a0002a0006a0007others(7): Show | a0002c0001a0002c0024a0002c0037others(16): Show | a0002c0001t0001a0002c0001t0005a0002c0001t0022others(26): Show | a0002c0001t0001g0100a0002c0001t0001g0103a0002c0001t0001g0108others(89): Show | 92 | 354 | 0 | ADAMTS14 | ENSG00000138316.11 | transcript | ENST00000373207.2 | protein_coding | 20/22 | c.3050G>A | p.Ser1017Asn | 3347/5557 | 3050/3672 | 1017/1223 | ||
|
chr10:70758253
|
A | G | 0.2655 | missense_variant | MODERATE | HG00099.hp2 HG00280.hp1 HG00408.hp2 others(91): Show |
a0002a0006a0007others(8): Show | a0002c0001a0002c0024a0002c0037others(17): Show | a0002c0001t0001a0002c0001t0005a0002c0001t0022others(28): Show | a0002c0001t0001g0100a0002c0001t0001g0103a0002c0001t0001g0108others(91): Show | 94 | 354 | 0 | ADAMTS14 | ENSG00000138316.11 | transcript | ENST00000373207.2 | protein_coding | 21/22 | c.3146A>G | p.Glu1049Gly | 3443/5557 | 3146/3672 | 1049/1223 |
| genename | grch38/chm13v2 1/0: The haplotype type is the same as GRCh380/1: The haplotype type is the same as CHM13v20/0: The haplotype type matches neither GRCh38 nor CHM13v21/1: The haplotype type is the same on both GRCh38 and CHM13v2
|
ahapid | alen | total | AFR | AMR | EAS | EUR | SAS | aseq | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADAMTS14 | 0/0 | a0002 | 1223 | 60 | 4 | 9 | 39 | 2 | 6 | subcellular location copy fasta | chr10 | 70667506 | 70767441 |
Click to load Haplotype QTL data...
| pos | S. Strand |
E# Exon Number |
max | median | min | diff | type | haplotypeid | max_hap_list | min_hap_list | symbol | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 70672884 | + | 1 | -0.9013 | -0.8990 | -0.8734 | 0.0279 | acceptor | a0002 | NA20905.hp1 | HG00099.hp2 HG00280.hp1 HG00741.hp1 HG01433.hp2 |
ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70674556 | + | 2 | 0.9709 | 0.9663 | 0.9636 | 0.0072 | donor | a0002 | HG00099.hp2 HG00280.hp1 HG00741.hp1 HG01433.hp2 |
NA18965.hp2 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70674995 | + | 2 | -0.9843 | -0.9814 | -0.9777 | 0.0066 | acceptor | a0002 | HG03130.hp1 | NA18965.hp2 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70702312 | + | 3 | 0.9967 | 0.9966 | 0.9965 | 0.0001 | donor | a0002 | NA19074.hp1 | HG02004.hp1 HG03669.hp1 NA18522.hp2 NA18965.hp2 NA18979.hp1 others(1): Show |
ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70702468 | + | 3 | -0.9982 | -0.9981 | -0.9981 | 0.0001 | acceptor | a0002 | HG02074.hp1 NA18950.hp1 |
HG00741.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70708588 | + | 4 | 0.9966 | 0.9963 | 0.9959 | 0.0007 | donor | a0002 | HG00099.hp2 HG00280.hp1 HG00639.hp2 HG00741.hp1 HG01433.hp2 |
HG01069.hp2 HG01071.hp2 |
ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70708778 | + | 4 | -0.9939 | -0.9932 | -0.9926 | 0.0012 | acceptor | a0002 | HG00408.hp2 HG02015.hp2 HG02074.hp1 HG02080.hp1 HG02129.hp1 others(9): Show |
HG03130.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70729294 | + | 5 | 0.9984 | 0.9984 | 0.9981 | 0.0004 | donor | a0002 | HG00280.hp1 HG03486.hp2 |
HG00741.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70729377 | + | 5 | -0.9972 | -0.9971 | -0.9968 | 0.0004 | acceptor | a0002 | HG00280.hp1 | NA19067.hp2 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70730102 | + | 6 | 0.9594 | 0.9583 | 0.9535 | 0.0059 | donor | a0002 | HG03486.hp2 | NA18522.hp2 NA18979.hp1 |
ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70730249 | + | 6 | -0.9224 | -0.9209 | -0.9130 | 0.0093 | acceptor | a0002 | NA18522.hp2 NA18979.hp1 |
HG02004.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70732254 | + | 7 | 0.9901 | 0.9893 | 0.9886 | 0.0015 | donor | a0002 | NA18522.hp2 NA18979.hp1 |
HG03130.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70732359 | + | 7 | -0.9969 | -0.9966 | -0.9963 | 0.0005 | acceptor | a0002 | NA18522.hp2 NA18979.hp1 |
HG00280.hp1 HG03486.hp2 |
ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70733885 | + | 8 | 0.9695 | 0.9664 | 0.9640 | 0.0056 | donor | a0002 | HG01069.hp2 HG01071.hp2 |
HG03130.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70734028 | + | 8 | -0.9593 | -0.9429 | -0.9416 | 0.0176 | acceptor | a0002 | HG01069.hp2 HG01071.hp2 |
HG02074.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70735169 | + | 9 | 0.9975 | 0.9975 | 0.9973 | 0.0002 | donor | a0002 | HG02074.hp1 | NA18994.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70735301 | + | 9 | -0.9956 | -0.9951 | -0.9944 | 0.0012 | acceptor | a0002 | HG02074.hp1 | NA18960.hp2 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70736680 | + | 10 | 0.9387 | 0.9353 | 0.9295 | 0.0091 | donor | a0002 | NA18522.hp2 NA18979.hp1 |
NA18994.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70736793 | + | 10 | -0.9846 | -0.9804 | -0.9783 | 0.0063 | acceptor | a0002 | HG02074.hp1 | NA18522.hp2 NA18979.hp1 |
ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70738842 | + | 11 | 0.8231 | 0.8193 | 0.8117 | 0.0114 | donor | a0002 | HG02074.hp1 | NA18522.hp2 NA18979.hp1 |
ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70738990 | + | 11 | -0.9012 | -0.9000 | -0.8838 | 0.0174 | acceptor | a0002 | NA19058.hp2 NA19084.hp2 |
NA18994.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70740987 | + | 12 | 0.9929 | 0.9929 | 0.9921 | 0.0008 | donor | a0002 | HG03669.hp1 | NA18994.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70741162 | + | 12 | -0.9984 | -0.9984 | -0.9983 | 0.0001 | acceptor | a0002 | NA19058.hp2 NA19084.hp2 |
NA18994.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70743548 | + | 13 | 0.9962 | 0.9960 | 0.9955 | 0.0007 | donor | a0002 | HG01099.hp2 HG03225.hp1 HG03486.hp2 |
NA18522.hp2 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70743681 | + | 13 | -0.9507 | -0.9506 | -0.9396 | 0.0111 | acceptor | a0002 | NA18994.hp1 | NA18522.hp2 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70744066 | + | 14 | 0.9778 | 0.9777 | 0.9688 | 0.0090 | donor | a0002 | HG01099.hp2 HG03225.hp1 HG03486.hp2 |
NA18522.hp2 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70744189 | + | 14 | -0.9926 | -0.9925 | -0.9910 | 0.0016 | acceptor | a0002 | HG01099.hp2 HG03225.hp1 HG03486.hp2 |
NA18522.hp2 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70745226 | + | 15 | 0.9818 | 0.9791 | 0.9786 | 0.0032 | donor | a0002 | NA18979.hp1 | HG00741.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70745306 | + | 15 | -0.9874 | -0.9845 | -0.9842 | 0.0032 | acceptor | a0002 | NA18522.hp2 | HG03130.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70749822 | + | 16 | 0.9180 | 0.9168 | 0.8957 | 0.0223 | donor | a0002 | HG00609.hp2 HG02027.hp1 |
HG03669.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70749985 | + | 16 | -0.9962 | -0.9942 | -0.9939 | 0.0022 | acceptor | a0002 | HG02004.hp1 | HG00609.hp2 HG02027.hp1 |
ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70751478 | + | 17 | 0.9566 | 0.9518 | 0.9497 | 0.0069 | donor | a0002 | NA18522.hp2 | HG00408.hp2 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70751646 | + | 17 | -0.9912 | -0.9887 | -0.9883 | 0.0029 | acceptor | a0002 | HG02004.hp1 | HG01952.hp2 HG02148.hp2 NA20905.hp1 |
ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70752095 | + | 18 | 0.9746 | 0.9683 | 0.9681 | 0.0065 | donor | a0002 | HG03669.hp1 | NA18979.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70752227 | + | 18 | -0.9934 | -0.9933 | -0.9924 | 0.0010 | acceptor | a0002 | NA18950.hp1 | HG02004.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70753800 | + | 19 | 0.9758 | 0.9742 | 0.9663 | 0.0096 | donor | a0002 | NA18522.hp2 | HG03130.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70754007 | + | 19 | -0.9456 | -0.9409 | -0.9250 | 0.0206 | acceptor | a0002 | HG03831.hp1 | HG03669.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70757962 | + | 20 | 0.8837 | 0.8817 | 0.8797 | 0.0040 | donor | a0002 | HG03927.hp2 | HG03669.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70758091 | + | 20 | -0.9593 | -0.9589 | -0.9580 | 0.0013 | acceptor | a0002 | HG03831.hp1 | NA19054.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70758175 | + | 21 | 0.9966 | 0.9965 | 0.9965 | 0.0001 | donor | a0002 | NA19054.hp1 | HG03831.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70758285 | + | 21 | -0.9967 | -0.9967 | -0.9966 | 0.0001 | acceptor | a0002 | HG03927.hp2 NA18522.hp2 |
HG03831.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| 70760360 | + | 22 | 0.9667 | 0.9666 | 0.9634 | 0.0033 | donor | a0002 | NA18941.hp1 NA18965.hp2 NA18973.hp1 NA19004.hp2 |
NA19054.hp1 | ADAMTS14 | chr10 | 70667506 | 70767441 |
| pos | annotationhgvs_chgvs_p | clinvarid | clnsig | geneinfo | mc | clndisdb | strand strand
|
ahapid ahapid_count
|
chapid chapid count
|
thapid thapid_count
|
ghapid ghapid_count
|
AHAPIDS ahapids
|
ACHAPIDS achapids
|
ACTHAPIDS acthapids
|
ACTGHAPIDS actghapids
|
haplotypeids haplotypeids
|
impact | chr | ref | alt | external |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 70758253:splice 70758253:variant goto | c.3146A>Gp.Glu1049Gly | 1287457 | Benign | ADAMTS14:140766 | SO:0001583 missense_variant |
MedGen:C3661900 | + | 11 | 20 | 31 | 94 | a0002a0006a0007a0008a0011others(6): Show | a0002c0001a0002c0024a0002c0037a0002c0040a0002c0084others(15): Show | a0002c0001t0001a0002c0001t0005a0002c0001t0022a0002c0001t0035a0002c0001t0036others(26): Show | a0002c0001t0001g0100a0002c0001t0001g0103a0002c0001t0001g0108a0002c0001t0001g0128a0002c0001t0001g0133others(89): Show | HG00099.hp2 HG00280.hp1 HG00408.hp2 HG00423.hp2 HG00597.hp2 others(89): Show |
MODERATE | chr10 | A | G | TogoVar |
| 70708643:splice 70708643:variant goto | c.735C>Tp.Gly245Gly | 788428 | Benign | ADAMTS14:140766 | SO:0001819 synonymous_variant |
MedGen:C3661900 | + | 1 | 1 | 1 | 1 | a0002 | a0002c0084 | a0002c0084t0001 | a0002c0084t0001g0334 | HG03130.hp1 | LOW | chr10 | C | T | TogoVar |
| CHR:POS | annotationhgvs_chgvs_p | disease trait-log10podds or beta | AHAPIDS ahapids
|
ACHAPIDS achapids
|
ACTHAPIDS acthapids
|
ACTGHAPIDS actghapids
|
haplotypeids haplotypeids
|
study | initial sample size/replication sample size | report genes | mapped gene | strongest snp risk allele | strand strand
|
impact | chr | ref | alt |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
chr10:70703238
|
c.679+770C>A | Bipolar disorder | a0001a0002a0003a0004a0005others(5): Show | a0001c0002a0001c0004a0001c0012a0001c0018a0001c0025others(15): Show | a0001c0002t0002a0001c0002t0018a0001c0004t0009a0001c0012t0009a0001c0018t0040others(18): Show | a0001c0002t0002g0130a0001c0002t0018g0090a0001c0002t0018g0095a0001c0004t0009g0088a0001c0012t0009g0003others(26): Show | HG00323.hp1 HG00597.hp1 HG01081.hp2 HG01109.hp1 HG01167.hp2 others(26): Show |
Propensity score-based nonparametric test revealin others(47): Show |
1,868 European ancestry cases, 2,938 European ance others(14): Show |
NR | ADAMTS14 | rs17600642-? | + | MODIFIER | chr10 | C | A |
|
chr10:70723254
|
c.871-6040T>C | Weight2.08 | a0001a0002a0003a0004a0005others(20): Show | a0001c0002a0001c0004a0001c0005a0001c0007a0001c0012others(66): Show | a0001c0002t0002a0001c0002t0007a0001c0002t0013a0001c0002t0041a0001c0004t0003others(99): Show | a0001c0002t0002g0110a0001c0002t0002g0116a0001c0002t0002g0130a0001c0002t0002g0131a0001c0002t0002g0147others(195): Show | HG00323.hp1 HG00323.hp2 HG00408.hp1 HG00408.hp2 HG00423.hp1 others(196): Show |
Linkage and genome-wide association analysis of ob others(68): Show |
Up to 3,925 European individuals/ | NR | ADAMTS14 | rs1816002-G | + | MODIFIER | chr10 | T | C |
|
chr10:70741007
|
c.1769T>Cp.Leu590Pro | Sleep duration0.19 | a0001a0002a0004a0005a0007others(18): Show | a0001c0002a0001c0004a0001c0005a0001c0007a0001c0012others(66): Show | a0001c0002t0002a0001c0002t0007a0001c0002t0013a0001c0002t0014a0001c0002t0018others(117): Show | a0001c0002t0002g0110a0001c0002t0002g0113a0001c0002t0002g0116a0001c0002t0002g0130a0001c0002t0002g0131others(282): Show | HG00099.hp1 HG00099.hp2 HG00140.hp1 HG00140.hp2 HG00280.hp1 others(283): Show |
A genome-wide association study of sleep habits an others(11): Show |
2,278 European ancestry individuals/ | ADAMTS14 | ADAMTS14 | rs10823607-T | + | MODERATE | chr10 | T | C |
|
chr10:70728483
|
c.871-811G>T | Heel bone mineral density | a0001a0002a0003a0004a0007others(4): Show | a0001c0002a0001c0004a0001c0005a0001c0017a0001c0026others(12): Show | a0001c0002t0002a0001c0004t0003a0001c0005t0006a0001c0017t0004a0001c0026t0002others(19): Show | a0001c0002t0002g0282a0001c0004t0003g0098a0001c0004t0003g0276a0001c0005t0006g0325a0001c0017t0004g0187others(58): Show | HG00099.hp2 HG00280.hp1 HG00558.hp1 HG00597.hp2 HG00609.hp2 others(59): Show |
Leveraging Polygenic Functional Enrichment to Impr others(15): Show |
approximately 446,000 European ancestry individual others(2): Show |
ADAMTS14 | rs4747090-? | + | MODIFIER | chr10 | G | T | |
|
chr10:70672291
|
c.-512G>A | Appendicular lean mass0.0733892 | a0001a0002a0003a0004a0005others(6): Show | a0001c0004a0001c0005a0001c0007a0001c0018a0001c0021others(16): Show | a0001c0004t0008a0001c0005t0026a0001c0007t0037a0001c0018t0008a0001c0018t0016others(22): Show | a0001c0004t0008g0050a0001c0005t0026g0069a0001c0007t0037g0029a0001c0018t0008g0034a0001c0018t0016g0023others(35): Show | HG00099.hp2 HG00280.hp1 HG00639.hp2 HG00741.hp1 HG01069.hp1 others(35): Show |
Genome-wide Associations Reveal Human-Mouse Geneti others(58): Show |
181,862 European ancestry elderly individuals/ | NR | PALD1 - ADAMTS14 | rs68049170-A | + | MODIFIER | chr10 | G | A |
|
chr10:70750053
|
c.2427+68C>T |
OTU97_138 (Oscillibacter) prevalence0.17 others(6): Show |
a0001a0002a0003a0004a0006others(14): Show | a0001c0002a0001c0004a0001c0005a0001c0007a0001c0012others(31): Show | a0001c0002t0002a0001c0002t0007a0001c0002t0013a0001c0002t0014a0001c0002t0018others(55): Show | a0001c0002t0002g0110a0001c0002t0002g0113a0001c0002t0002g0116a0001c0002t0002g0130a0001c0002t0002g0131others(114): Show | HG00099.hp1 HG00140.hp1 HG00140.hp2 HG00280.hp2 HG00544.hp1 others(115): Show |
Genome-wide association study in 8,956 German indi others(73): Show |
8,956 German ancestry individuals/ | ADAMTS14 | rs2541229-? | + | MODIFIER | chr10 | C | T | |
|
chr10:70746402
|
c.2263+1096C>A | Optic disc size0.01 | a0001a0002a0003a0004a0005others(17): Show | a0001c0004a0001c0005a0001c0007a0001c0017a0001c0019others(50): Show | a0001c0004t0003a0001c0004t0008a0001c0004t0009a0001c0004t0057a0001c0005t0011others(73): Show | a0001c0004t0003g0097a0001c0004t0003g0098a0001c0004t0003g0129a0001c0004t0003g0134a0001c0004t0003g0138others(179): Show | HG00099.hp2 HG00280.hp1 HG00323.hp1 HG00323.hp2 HG00408.hp1 others(180): Show |
Genome-wide association analysis of 95549 individu others(70): Show |
67,040 British ancestry individuals/28,509 Europea others(22): Show |
ADAMTS14 | ADAMTS14 | rs10823610-A | + | MODIFIER | chr10 | C | A |
|
chr10:70672291
|
c.-512G>A | Waist circumference adjusted for body mass indexothers(8): Show | a0001a0002a0003a0004a0005others(6): Show | a0001c0004a0001c0005a0001c0007a0001c0018a0001c0021others(16): Show | a0001c0004t0008a0001c0005t0026a0001c0007t0037a0001c0018t0008a0001c0018t0016others(22): Show | a0001c0004t0008g0050a0001c0005t0026g0069a0001c0007t0037g0029a0001c0018t0008g0034a0001c0018t0016g0023others(35): Show | HG00099.hp2 HG00280.hp1 HG00639.hp2 HG00741.hp1 HG01069.hp1 others(35): Show |
Shared Genetic and Experimental Links between Obes others(53): Show |
457,690 European ancestry individuals/ | NR | PALD1 - ADAMTS14 | rs68049170-? | + | MODIFIER | chr10 | G | A |
|
chr10:70673269
|
c.82+385G>A | Appendicular lean mass0.0706506 | a0001a0002a0003a0004a0005others(11): Show | a0001c0002a0001c0004a0001c0005a0001c0007a0001c0018others(29): Show | a0001c0002t0007a0001c0002t0020a0001c0002t0051a0001c0004t0008a0001c0005t0026others(39): Show | a0001c0002t0007g0009a0001c0002t0007g0010a0001c0002t0007g0011a0001c0002t0020g0068a0001c0002t0051g0067others(61): Show | HG00099.hp2 HG00280.hp1 HG00423.hp2 HG00609.hp1 HG00639.hp2 others(61): Show |
Genome-wide Associations Reveal Human-Mouse Geneti others(58): Show |
85,750 European ancestry middle-aged adult individ others(5): Show |
NR | ADAMTS14 | rs34616741-A | + | MODIFIER | chr10 | G | A |
|
chr10:70705732
|
c.680-2856A>G | Lobe attachment (rater-scored or self-reported)others(7): Show | a0001a0002a0003a0004a0005others(18): Show | a0001c0002a0001c0004a0001c0005a0001c0007a0001c0012others(58): Show | a0001c0002t0002a0001c0002t0018a0001c0002t0034a0001c0002t0041a0001c0004t0003others(87): Show | a0001c0002t0002g0130a0001c0002t0002g0220a0001c0002t0002g0222a0001c0002t0002g0281a0001c0002t0002g0282others(169): Show | HG00099.hp2 HG00280.hp1 HG00280.hp2 HG00323.hp1 HG00544.hp1 others(171): Show |
Multiethnic GWAS Reveals Polygenic Architecture of others(20): Show |
66,741 European ancestry individuals, 5,062 Hispan others(55): Show |
NR | ADAMTS14 | rs4746059-? | + | MODIFIER | chr10 | A | G |
|
chr10:70672291
|
c.-512G>A | Appendicular lean mass0.0259 | a0001a0002a0003a0004a0005others(6): Show | a0001c0004a0001c0005a0001c0007a0001c0018a0001c0021others(16): Show | a0001c0004t0008a0001c0005t0026a0001c0007t0037a0001c0018t0008a0001c0018t0016others(22): Show | a0001c0004t0008g0050a0001c0005t0026g0069a0001c0007t0037g0029a0001c0018t0008g0034a0001c0018t0016g0023others(35): Show | HG00099.hp2 HG00280.hp1 HG00639.hp2 HG00741.hp1 HG01069.hp1 others(35): Show |
The genetic architecture of appendicular lean mass others(63): Show |
450,243 European ancestry individuals/ | ADAMTS14 | PALD1 - ADAMTS14 | rs68049170-A | + | MODIFIER | chr10 | G | A |
|
chr10:70680191
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c.522+5196G>C | Left ventricular mass indexed by body surface areaothers(14): Show | a0001a0002a0003a0004a0005others(6): Show | a0001c0002a0001c0004a0001c0005a0001c0007a0001c0012others(29): Show | a0001c0002t0013a0001c0002t0018a0001c0002t0020a0001c0002t0041a0001c0002t0051others(37): Show | a0001c0002t0013g0341a0001c0002t0018g0090a0001c0002t0018g0095a0001c0002t0020g0068a0001c0002t0041g0075others(50): Show | HG00323.hp1 HG00639.hp1 HG00738.hp1 HG01069.hp2 HG01071.hp2 others(50): Show |
Clinical and genetic associations of deep learning others(64): Show |
41,855 European ancestry individuals, 577 Asian or others(102): Show |
ADAMTS14 | rs12253621-G | + | MODIFIER | chr10 | G | C | |
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chr10:70753926
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c.2856C>Tp.Cys952Cys | Serum cobalt levels0.153 | a0001a0002a0003a0004a0005others(15): Show | a0001c0002a0001c0005a0001c0012a0001c0019a0001c0025others(49): Show | a0001c0002t0002a0001c0002t0007a0001c0002t0013a0001c0002t0014a0001c0002t0018others(86): Show | a0001c0002t0002g0110a0001c0002t0002g0113a0001c0002t0002g0116a0001c0002t0002g0130a0001c0002t0002g0131others(187): Show | HG00099.hp1 HG00140.hp1 HG00140.hp2 HG00280.hp2 HG00408.hp1 others(189): Show |
Genome-wide association and Mendelian randomizatio others(65): Show |
1,758 East Asian ancestry individuals/ | ADAMTS14 | rs2587475-T | + | LOW | chr10 | C | T | |
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chr10:70721339
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c.871-7955C>A | Periodontal pocket (adjusted for age, sex and smoking status)others(21): Show | a0001a0002a0003a0004a0005others(8): Show | a0001c0002a0001c0004a0001c0007a0001c0012a0001c0017others(26): Show | a0001c0002t0002a0001c0002t0018a0001c0004t0003a0001c0004t0009a0001c0007t0021others(35): Show | a0001c0002t0002g0130a0001c0002t0002g0220a0001c0002t0002g0222a0001c0002t0002g0281a0001c0002t0002g0282others(74): Show | HG00323.hp1 HG00544.hp1 HG00558.hp1 HG00597.hp1 HG00597.hp2 others(75): Show |
Genome-wide association study of periodontal pocke others(23): Show |
3,906 Finnish ancestry individuals/ | ADAMTS14 | rs72814570-A | + | MODIFIER | chr10 | C | A | |
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chr10:70738541
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c.1600-301G>A | Heel bone mineral density0.0216129 | a0001a0002 | a0001c0017a0002c0001 | a0001c0017t0004a0002c0001t0005a0002c0001t0036 | a0001c0017t0004g0187a0002c0001t0005g0021a0002c0001t0005g0024a0002c0001t0005g0037a0002c0001t0005g0055others(1): Show | HG00099.hp2 HG00280.hp1 HG00639.hp2 HG00741.hp1 HG01123.hp2 others(1): Show |
An atlas of genetic influences on osteoporosis in others(16): Show |
426,824 British ancestry individuals/ | ADAMTS14 | ADAMTS14 | rs79999320-G | + | MODIFIER | chr10 | G | A |
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chr10:70735022
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c.1353-147G>A | Spontaneous preterm birth (preterm birth)others(4): Show | a0001a0002a0003a0004a0005others(22): Show | a0001c0002a0001c0004a0001c0005a0001c0007a0001c0012others(72): Show | a0001c0002t0002a0001c0002t0007a0001c0002t0013a0001c0002t0014a0001c0002t0018others(120): Show | a0001c0002t0002g0110a0001c0002t0002g0113a0001c0002t0002g0116a0001c0002t0002g0130a0001c0002t0002g0131others(282): Show | HG00099.hp1 HG00099.hp2 HG00140.hp1 HG00140.hp2 HG00280.hp1 others(283): Show |
Risk of spontaneous preterm birth and fetal growth others(29): Show |
247 Finnish ancestry infant cases, 419 Finnish anc others(22): Show |
ADAMTS14 | rs12765664-? | + | MODIFIER | chr10 | G | A | |
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chr10:70740752
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c.1749-235A>T | Moderate-to-late spontaneous preterm birthothers(10): Show | a0001a0002a0004a0005a0007others(18): Show | a0001c0002a0001c0004a0001c0005a0001c0007a0001c0012others(66): Show | a0001c0002t0002a0001c0002t0007a0001c0002t0013a0001c0002t0014a0001c0002t0018others(116): Show | a0001c0002t0002g0110a0001c0002t0002g0113a0001c0002t0002g0116a0001c0002t0002g0130a0001c0002t0002g0131others(278): Show | HG00099.hp1 HG00099.hp2 HG00140.hp1 HG00140.hp2 HG00280.hp1 others(279): Show |
Risk of spontaneous preterm birth and fetal growth others(29): Show |
75 Finnish ancestry infant cases, 419 Finnish ance others(21): Show |
ADAMTS14 | ADAMTS14 | rs7093347-? | + | MODIFIER | chr10 | A | T |
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chr10:70735022
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c.1353-147G>A | Spontaneous preterm birth with premature rupture of membranesothers(30): Show | a0001a0002a0003a0004a0005others(22): Show | a0001c0002a0001c0004a0001c0005a0001c0007a0001c0012others(72): Show | a0001c0002t0002a0001c0002t0007a0001c0002t0013a0001c0002t0014a0001c0002t0018others(120): Show | a0001c0002t0002g0110a0001c0002t0002g0113a0001c0002t0002g0116a0001c0002t0002g0130a0001c0002t0002g0131others(282): Show | HG00099.hp1 HG00099.hp2 HG00140.hp1 HG00140.hp2 HG00280.hp1 others(283): Show |
Risk of spontaneous preterm birth and fetal growth others(29): Show |
133 Finnish ancestry infant cases, 419 Finnish anc others(22): Show |
ADAMTS14 | ADAMTS14 | rs12765664-? | + | MODIFIER | chr10 | G | A |
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chr10:70672742
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c.-61C>A | Carpal tunnel syndrome1.05359 | a0001a0002a0003a0004a0005others(13): Show | a0001c0002a0001c0004a0001c0005a0001c0007a0001c0012others(38): Show | a0001c0002t0007a0001c0002t0018a0001c0002t0020a0001c0002t0041a0001c0002t0051others(58): Show | a0001c0002t0007g0009a0001c0002t0007g0010a0001c0002t0007g0011a0001c0002t0018g0090a0001c0002t0018g0095others(89): Show | HG00099.hp2 HG00280.hp1 HG00423.hp2 HG00609.hp1 HG00639.hp2 others(89): Show |
A genome-wide meta-analysis identifies 50 genetic others(44): Show |
48,843 European ancestry cases, 1,190,837 European others(19): Show |
ADAMTS14 | rs12762780-C | + | MODIFIER | chr10 | C | A | |
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chr10:70695884
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c.523-6428T>C | Gut microbial network clusters (Salmon (at 1 year) x Spring Birth (Mar-May) interactionothers(51): Show | a0001a0002 | a0001c0017a0001c0019a0002c0001 | a0001c0017t0004a0001c0019t0009a0002c0001t0005a0002c0001t0036 | a0001c0017t0004g0187a0001c0019t0009g0074a0002c0001t0005g0021a0002c0001t0005g0037a0002c0001t0005g0055others(1): Show | HG00099.hp2 HG00280.hp1 HG00639.hp2 HG01123.hp2 HG01257.hp2 others(1): Show |
Gene-by-environment interactions modulate the infa others(38): Show |
688 European ancestry, South Asian ancestry, East others(231): Show |
ADAMTS14 | rs76525388-C | + | MODIFIER | chr10 | T | C | |
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chr10:70764716
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c.*3863C>G | Glioblastoma3.1912096 | a0001a0002a0020 | a0001c0002a0002c0001a0020c0053 | a0001c0002t0024a0002c0001t0036a0020c0053t0024 | a0001c0002t0024g0205a0001c0002t0024g0213a0002c0001t0036g0038a0020c0053t0024g0204 | HG00099.hp1 HG00099.hp2 HG00735.hp1 NA20805.hp1 |
Multi-ancestry genome-wide association study of 4, others(54): Show |
90 European ancestry cases, 7,183 European ancestr others(294): Show |
ADAMTS14 - TBATA | rs78036371-? | + | MODIFIER | chr10 | C | G |