| geneid | 79719 |
|---|---|
| ensemblid | ENSG00000103591.13 |
| hgncid | 25662 |
| symbol | AAGAB |
| name | alpha and gamma adaptin binding protein |
| refseq_nuc | NM_024666.5 |
| refseq_prot | NP_078942.3 |
| ensembl_nuc | ENST00000261880.10 |
| ensembl_prot | ENSP00000261880.5 |
| mane_status | MANE Select |
| chr | chr15 |
| start | 67200667 |
| end | 67254661 |
| strand | - |
| ver | v1.2 |
| region | chr15:67200667-67254661 |
| region5000 | chr15:67195667-67259661 |
| regionname0 | AAGAB_chr15_67200667_67254661 |
| regionname5000 | AAGAB_chr15_67195667_67259661 |
| chr:pos | ref | alt | af | annotation | impact | samples | AHAPIDS | ACHAPIDS | ACTHAPIDS | ACTGHAPIDS | ac | an | len | genename | geneid | featuretype | featureid | transcript_biotype | rank | hgvs_c | hgvs_p | cdna_pos_length | cds_pos_length | aa_pos_length | distance | status |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
chr15:67236036
|
T | G | 0.4421 | missense_variant | MODERATE | HG00280.hp2 HG00438.hp1 HG00438.hp2 others(165): Show |
a0002a0005 | a0002c0002a0005c0007 | a0002c0002t0001a0002c0002t0002a0002c0002t0003others(5): Show | a0002c0002t0001g0151a0002c0002t0001g0336a0002c0002t0002g0004others(161): Show | 168 | 380 | 0 | AAGAB | ENSG00000103591.13 | transcript | ENST00000261880.10 | protein_coding | 4/10 | c.394A>C | p.Ile132Leu | 424/3132 | 394/948 | 132/315 |
| chr:pos | ref | alt | af | annotation | impact | samples | ahapids | achapids | acthapids | actghapids | ac | an | len | genename | geneid | featuretype | featureid | transcript_biotype | rank | hgvs_c | hgvs_p | cdna_pos_length | cds_pos_length | aa_pos_length | distance | status |
|---|
| chr:pos | ref | alt | af | annotation | impact | samples | ahapids | achapids | acthapids | actghapids | ac | an | len | genename | geneid | featuretype | featureid | transcript_biotype | rank | hgvs_c | hgvs_p | cdna_pos_length | cds_pos_length | aa_pos_length | distance | status |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
chr15:67201289
|
G | GA | 0.2895 | 3_prime_UTR_variant | MODIFIER | HG00280.hp2 HG00438.hp2 HG00544.hp2 others(107): Show |
a0001a0002 | a0001c0001a0002c0002 | a0001c0001t0011a0001c0001t0015a0001c0001t0017others(2): Show | a0001c0001t0011g0012a0001c0001t0015g0253a0001c0001t0017g0258others(104): Show | 110 | 380 | 1 | AAGAB | ENSG00000103591.13 | transcript | ENST00000261880.10 | protein_coding | 10/10 | c.*1531dupT | 1531 | |||||
|
chr15:67201388
|
T | C | 0.2816 | 3_prime_UTR_variant | MODIFIER | HG00280.hp2 HG00438.hp2 HG00544.hp2 others(104): Show |
a0001a0002 | a0001c0001a0002c0002 | a0001c0001t0020a0002c0002t0003a0002c0002t0007 | a0001c0001t0020g0023a0002c0002t0003g0007a0002c0002t0003g0008others(102): Show | 107 | 380 | 0 | AAGAB | ENSG00000103591.13 | transcript | ENST00000261880.10 | protein_coding | 10/10 | c.*1433A>G | 1433 | |||||
|
chr15:67202485
|
G | C | 0.2947 | 3_prime_UTR_variant | MODIFIER | HG00280.hp2 HG00438.hp2 HG00544.hp2 others(109): Show |
a0001a0002 | a0001c0001a0002c0002 | a0001c0001t0006a0001c0001t0020a0002c0002t0003others(2): Show | a0001c0001t0006g0236a0001c0001t0006g0237a0001c0001t0006g0238others(107): Show | 112 | 380 | 0 | AAGAB | ENSG00000103591.13 | transcript | ENST00000261880.10 | protein_coding | 10/10 | c.*336C>G | 336 | |||||
|
chr15:67202584
|
T | C | 0.2763 | 3_prime_UTR_variant | MODIFIER | HG00280.hp2 HG00438.hp2 HG00544.hp2 others(102): Show |
a0002 | a0002c0002 | a0002c0002t0003a0002c0002t0013 | a0002c0002t0003g0007a0002c0002t0003g0008a0002c0002t0003g0132others(100): Show | 105 | 380 | 0 | AAGAB | ENSG00000103591.13 | transcript | ENST00000261880.10 | protein_coding | 10/10 | c.*237A>G | 237 |
| genename | grch38/chm13v2 1/0: The haplotype type is the same as GRCh380/1: The haplotype type is the same as CHM13v20/0: The haplotype type matches neither GRCh38 nor CHM13v21/1: The haplotype type is the same on both GRCh38 and CHM13v2
|
ahapid | alen | total | AFR | AMR | EAS | EUR | SAS | aseq | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AAGAB | 0/0 | a0002 | 315 | 167 | 9 | 26 | 109 | 6 | 17 | subcellular location copy fasta | chr15 | 67195667 | 67259661 |
| genename | grch38/chm13v2 1/0: The haplotype type is the same as GRCh380/1: The haplotype type is the same as CHM13v20/0: The haplotype type matches neither GRCh38 nor CHM13v21/1: The haplotype type is the same on both GRCh38 and CHM13v2
|
chapid | clen | total | AFR | AMR | EAS | EUR | SAS | cseq | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AAGAB | 0/0 | c0002 | 948 | 167 | 9 | 26 | 109 | 6 | 17 | copy fasta | chr15 | 67195667 | 67259661 |
| genename | grch38/chm13v2 | thapid | tlen | total | AFR | AMR | EAS | EUR | SAS | tseq | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AAGAB | 0/0 | t0003 | 2186 | 103 | 5 | 24 | 60 | 5 | 9 | copy fasta | chr15 | 67195667 | 67259661 |
| genename | grch38/chm13v2 1/0: The haplotype type is the same as GRCh380/1: The haplotype type is the same as CHM13v20/0: The haplotype type matches neither GRCh38 nor CHM13v21/1: The haplotype type is the same on both GRCh38 and CHM13v2 |
achapid | total | AFR | AMR | EAS | EUR | SAS | clen | cseq | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AAGAB | 0/0 | a0002c0002 | 167 | 9 | 26 | 109 | 6 | 17 | 948 | copy fasta | chr15 | 67195667 | 67259661 |
| genename | grch38/chm13v2 1/0: The haplotype type is the same as GRCh380/1: The haplotype type is the same as CHM13v20/0: The haplotype type matches neither GRCh38 nor CHM13v21/1: The haplotype type is the same on both GRCh38 and CHM13v2 |
acthapid | total | AFR | AMR | EAS | EUR | SAS | tlen | tseq | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AAGAB | 0/0 | a0002c0002t0003 | 103 | 5 | 24 | 60 | 5 | 9 | 3133 | copy fasta | chr15 | 67195667 | 67259661 |
Click to load Haplotype QTL data...
| pos | S. Strand |
E# Exon Number |
max | median | min | diff | type | haplotypeid | max_hap_list | min_hap_list | symbol | chr | start | end |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 67254559 | - | 1 | -0.6809 | -0.6655 | -0.6437 | 0.0372 | acceptor | a0002c0002t0003 | HG04115.hp1 | HG02129.hp2 | AAGAB | chr15 | 67195667 | 67259661 |
| 67236630 | - | 2 | -0.9898 | -0.9898 | -0.9885 | 0.0014 | acceptor | a0002c0002t0003 | NA18960.hp2 | HG02132.hp1 | AAGAB | chr15 | 67195667 | 67259661 |
| 67236820 | - | 2 | 0.9985 | 0.9984 | 0.9983 | 0.0002 | donor | a0002c0002t0003 | NA18953.hp2 | HG01081.hp1 HG01255.hp2 HG01943.hp1 HG02132.hp1 NA18747.hp2 others(2): Show |
AAGAB | chr15 | 67195667 | 67259661 |
| 67236408 | - | 3 | -0.9833 | -0.9831 | -0.9825 | 0.0008 | acceptor | a0002c0002t0003 | HG04184.hp1 NA18979.hp1 NA19054.hp2 NA19055.hp2 |
HG02132.hp1 | AAGAB | chr15 | 67195667 | 67259661 |
| 67236504 | - | 3 | 0.9744 | 0.9741 | 0.9704 | 0.0040 | donor | a0002c0002t0003 | NA19060.hp2 | HG02132.hp1 | AAGAB | chr15 | 67195667 | 67259661 |
| 67235979 | - | 4 | -0.9966 | -0.9964 | -0.9964 | 0.0001 | acceptor | a0002c0002t0003 | NA18953.hp2 | NA19060.hp2 | AAGAB | chr15 | 67195667 | 67259661 |
| 67236068 | - | 4 | 0.9954 | 0.9953 | 0.9950 | 0.0004 | donor | a0002c0002t0003 | HG01081.hp1 HG01255.hp2 HG01943.hp1 NA18747.hp2 NA19075.hp2 others(1): Show |
HG01981.hp2 HG02148.hp2 HG02486.hp2 HG04115.hp1 NA18966.hp1 others(3): Show |
AAGAB | chr15 | 67195667 | 67259661 |
| 67231814 | - | 5 | -0.9832 | -0.9814 | -0.9812 | 0.0020 | acceptor | a0002c0002t0003 | NA18984.hp2 | HG02486.hp2 | AAGAB | chr15 | 67195667 | 67259661 |
| 67231897 | - | 5 | 0.9636 | 0.9599 | 0.9562 | 0.0075 | donor | a0002c0002t0003 | NA19078.hp1 | HG01257.hp1 | AAGAB | chr15 | 67195667 | 67259661 |
| 67209462 | - | 6 | -0.9945 | -0.9943 | -0.9942 | 0.0003 | acceptor | a0002c0002t0003 | NA19054.hp2 | HG00438.hp2 HG00609.hp2 NA18940.hp1 NA18949.hp2 NA18959.hp1 others(8): Show |
AAGAB | chr15 | 67195667 | 67259661 |
| 67209544 | - | 6 | 0.9913 | 0.9894 | 0.9890 | 0.0023 | donor | a0002c0002t0003 | NA18960.hp2 | HG02132.hp1 NA18747.hp2 NA19075.hp2 |
AAGAB | chr15 | 67195667 | 67259661 |
| 67208562 | - | 7 | -0.9970 | -0.9970 | -0.9970 | 0.0000 | acceptor | a0002c0002t0003 | NA18960.hp2 NA19054.hp2 |
NA18963.hp1 | AAGAB | chr15 | 67195667 | 67259661 |
| 67208658 | - | 7 | 0.9853 | 0.9851 | 0.9850 | 0.0003 | donor | a0002c0002t0003 | HG02132.hp1 NA18747.hp2 NA19075.hp2 |
NA18960.hp2 | AAGAB | chr15 | 67195667 | 67259661 |
| 67204044 | - | 8 | -0.9703 | -0.9650 | -0.9547 | 0.0155 | acceptor | a0002c0002t0003 | NA18942.hp1 | NA19090.hp1 | AAGAB | chr15 | 67195667 | 67259661 |
| 67204148 | - | 8 | 0.8937 | 0.8912 | 0.8814 | 0.0123 | donor | a0002c0002t0003 | NA18942.hp1 | NA19090.hp1 | AAGAB | chr15 | 67195667 | 67259661 |
| 67203548 | - | 9 | -0.6916 | -0.6159 | -0.5772 | 0.1144 | acceptor | a0002c0002t0003 | NA19090.hp1 | HG01496.hp1 | AAGAB | chr15 | 67195667 | 67259661 |
| 67203597 | - | 9 | 0.7031 | 0.6982 | 0.6479 | 0.0552 | donor | a0002c0002t0003 | NA18942.hp1 | HG01496.hp1 | AAGAB | chr15 | 67195667 | 67259661 |
| 67202898 | - | 10 | 0.8582 | 0.8243 | 0.8124 | 0.0459 | donor | a0002c0002t0003 | NA19090.hp1 | HG01081.hp1 HG01255.hp2 HG01943.hp1 HG02132.hp1 NA18747.hp2 others(2): Show |
AAGAB | chr15 | 67195667 | 67259661 |
| CHR:POS | annotationhgvs_chgvs_p | disease trait-log10podds or beta | AHAPIDS ahapids
|
ACHAPIDS achapids
|
ACTHAPIDS acthapids
|
ACTGHAPIDS actghapids
|
haplotypeids haplotypeids
|
study | initial sample size/replication sample size | report genes | mapped gene | strongest snp risk allele | strand strand
|
impact | chr | ref | alt |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
chr15:67254963
|
c.-332G>T | Total body bone mineral density0.0519 | a0001a0002 | a0001c0001a0002c0002 | a0001c0001t0020a0001c0001t0021a0002c0002t0001a0002c0002t0003a0002c0002t0007others(1): Show | a0001c0001t0020g0023a0001c0001t0021g0025a0002c0002t0001g0151a0002c0002t0003g0007a0002c0002t0003g0008others(104): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(106): Show |
Life-Course Genome-wide Association Study Meta-ana others(63): Show |
56,284 European ancestry individuals, up to 1,333 others(62): Show |
NR | IQCH, AAGAB | rs3743347-A | - | MODIFIER | chr15 | C | A |
|
chr15:67236036
|
c.394A>Cp.Ile132Leu | Cardiovascular disease | a0002a0005 | a0002c0002a0005c0007 | a0002c0002t0001a0002c0002t0002a0002c0002t0003a0002c0002t0007a0002c0002t0012others(3): Show | a0002c0002t0001g0151a0002c0002t0001g0336a0002c0002t0002g0004a0002c0002t0002g0005a0002c0002t0002g0024others(159): Show | HG00280.hp2 HG00438.hp1 HG00438.hp2 HG00544.hp2 HG00558.hp1 others(163): Show |
Leveraging Polygenic Functional Enrichment to Impr others(15): Show |
approximately 459,000 European ancestry individual others(2): Show |
AAGAB | rs7173826-? | - | MODERATE | chr15 | T | G | |
|
chr15:67236036
|
c.394A>Cp.Ile132Leu | Waist-hip index0.0193774 | a0002a0005 | a0002c0002a0005c0007 | a0002c0002t0001a0002c0002t0002a0002c0002t0003a0002c0002t0007a0002c0002t0012others(3): Show | a0002c0002t0001g0151a0002c0002t0001g0336a0002c0002t0002g0004a0002c0002t0002g0005a0002c0002t0002g0024others(159): Show | HG00280.hp2 HG00438.hp1 HG00438.hp2 HG00544.hp2 HG00558.hp1 others(163): Show |
GWAS of allometric body-shape indices in UK Bioban others(109): Show |
186,825 British ancestry men/ | AAGAB | AAGAB | rs7173826-G | - | MODERATE | chr15 | T | G |
|
chr15:67236036
|
c.394A>Cp.Ile132Leu | Waist circumference adjusted for body mass indexothers(17): Show | a0002a0005 | a0002c0002a0005c0007 | a0002c0002t0001a0002c0002t0002a0002c0002t0003a0002c0002t0007a0002c0002t0012others(3): Show | a0002c0002t0001g0151a0002c0002t0001g0336a0002c0002t0002g0004a0002c0002t0002g0005a0002c0002t0002g0024others(159): Show | HG00280.hp2 HG00438.hp1 HG00438.hp2 HG00544.hp2 HG00558.hp1 others(163): Show |
GWAS of allometric body-shape indices in UK Bioban others(109): Show |
186,825 British ancestry men/ | AAGAB | AAGAB | rs7173826-G | - | MODERATE | chr15 | T | G |
|
chr15:67236036
|
c.394A>Cp.Ile132Leu |
Waist-to-hip ratio adjusted for BMI0.018 others(4): Show |
a0002a0005 | a0002c0002a0005c0007 | a0002c0002t0001a0002c0002t0002a0002c0002t0003a0002c0002t0007a0002c0002t0012others(3): Show | a0002c0002t0001g0151a0002c0002t0001g0336a0002c0002t0002g0004a0002c0002t0002g0005a0002c0002t0002g0024others(159): Show | HG00280.hp2 HG00438.hp1 HG00438.hp2 HG00544.hp2 HG00558.hp1 others(163): Show |
GWAS of allometric body-shape indices in UK Bioban others(109): Show |
186,825 British ancestry men/ | AAGAB | AAGAB | rs7173826-G | - | MODERATE | chr15 | T | G |
|
chr15:67254963
|
c.-332G>T | FVC or gastro-oesophageal reflux disease (pleiotropy)others(13): Show | a0001a0002 | a0001c0001a0002c0002 | a0001c0001t0020a0001c0001t0021a0002c0002t0001a0002c0002t0003a0002c0002t0007others(1): Show | a0001c0001t0020g0023a0001c0001t0021g0025a0002c0002t0001g0151a0002c0002t0003g0007a0002c0002t0003g0008others(104): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(106): Show |
Genetic and observational associations of lung fun others(93): Show |
400,102 European ancestry individuals with FVC mea others(82): Show |
IQCH, AAGAB | rs3743347-? | - | MODIFIER | chr15 | C | A | |
|
chr15:67207992
|
c.715+570A>G | FEV1 | a0002 | a0002c0002 | a0002c0002t0001a0002c0002t0003a0002c0002t0007a0002c0002t0013 | a0002c0002t0001g0151a0002c0002t0003g0007a0002c0002t0003g0008a0002c0002t0003g0132a0002c0002t0003g0133others(102): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(104): Show |
A genome-wide association study identifies distinc others(104): Show |
383,471 European ancestry individuals/ | AAGAB | rs4776905-? | - | MODIFIER | chr15 | T | C | |
|
chr15:67207992
|
c.715+570A>G | FVC | a0002 | a0002c0002 | a0002c0002t0001a0002c0002t0003a0002c0002t0007a0002c0002t0013 | a0002c0002t0001g0151a0002c0002t0003g0007a0002c0002t0003g0008a0002c0002t0003g0132a0002c0002t0003g0133others(102): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(104): Show |
A genome-wide association study identifies distinc others(104): Show |
383,471 European ancestry individuals/ | AAGAB | rs4776905-? | - | MODIFIER | chr15 | T | C | |
|
chr15:67243102
|
c.74-6282A>G | Estimated glomerular filtration rate (creatinine)others(14): Show | a0002 | a0002c0002 | a0002c0002t0001a0002c0002t0003a0002c0002t0013 | a0002c0002t0001g0151a0002c0002t0003g0007a0002c0002t0003g0008a0002c0002t0003g0132a0002c0002t0003g0133others(99): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(101): Show |
Epigenomic and transcriptomic analyses define core others(64): Show |
1,205,871 European ancestry individuals, 168,300 E others(384): Show |
AAGAB | rs12900708-C | - | MODIFIER | chr15 | T | C | |
|
chr15:67202584
|
c.*237A>G | Estimated glomerular filtration rate (creatinine)others(16): Show | a0002 | a0002c0002 | a0002c0002t0003a0002c0002t0013 | a0002c0002t0003g0007a0002c0002t0003g0008a0002c0002t0003g0132a0002c0002t0003g0133a0002c0002t0003g0135others(98): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(100): Show |
Discovery and prioritization of variants and genes others(49): Show |
1,004,040 European ancestry individuals, 165,726 E others(189): Show |
AAGAB | rs12148121-C | - | MODIFIER | chr15 | T | C | |
|
chr15:67198936
|
c.*3885G>T | Lung function (FVC)0.0228 | a0002 | a0002c0002 | a0002c0002t0003a0002c0002t0007a0002c0002t0013 | a0002c0002t0003g0007a0002c0002t0003g0008a0002c0002t0003g0132a0002c0002t0003g0133a0002c0002t0003g0135others(99): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(101): Show |
New genetic signals for lung function highlight pa others(89): Show |
321,047 European ancestry individuals/79,005 Europ others(24): Show |
AAGAB | SMAD3 - AAGAB | rs12917612-A | - | MODIFIER | chr15 | C | A |
|
chr15:67198936
|
c.*3885G>T | FEV10.0136 | a0002 | a0002c0002 | a0002c0002t0003a0002c0002t0007a0002c0002t0013 | a0002c0002t0003g0007a0002c0002t0003g0008a0002c0002t0003g0132a0002c0002t0003g0133a0002c0002t0003g0135others(99): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(101): Show |
New genetic signals for lung function highlight pa others(89): Show |
321,047 European ancestry individuals/79,005 Europ others(24): Show |
AAGAB | SMAD3 - AAGAB | rs12917612-A | - | MODIFIER | chr15 | C | A |
|
chr15:67198936
|
c.*3885G>T | Lung function (FEV1/FVC)0.0141 | a0002 | a0002c0002 | a0002c0002t0003a0002c0002t0007a0002c0002t0013 | a0002c0002t0003g0007a0002c0002t0003g0008a0002c0002t0003g0132a0002c0002t0003g0133a0002c0002t0003g0135others(99): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(101): Show |
New genetic signals for lung function highlight pa others(89): Show |
321,047 European ancestry individuals/79,005 Europ others(24): Show |
AAGAB | SMAD3 - AAGAB | rs12917612-A | - | MODIFIER | chr15 | C | A |
|
chr15:67218266
|
c.536-8722C>G | Whole body fat mass (UKB data field 23100)others(11): Show | a0002 | a0002c0002 | a0002c0002t0001a0002c0002t0003a0002c0002t0007a0002c0002t0013 | a0002c0002t0001g0151a0002c0002t0003g0007a0002c0002t0003g0008a0002c0002t0003g0132a0002c0002t0003g0133others(102): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(104): Show |
New role of fat-free mass in cancer risk linked wi others(26): Show |
337,196 European ancestry individuals/ | AAGAB | rs16950776-C | - | MODIFIER | chr15 | G | C | |
|
chr15:67236036
|
c.394A>Cp.Ile132Leu | A body shape index0.0195852 | a0002a0005 | a0002c0002a0005c0007 | a0002c0002t0001a0002c0002t0002a0002c0002t0003a0002c0002t0007a0002c0002t0012others(3): Show | a0002c0002t0001g0151a0002c0002t0001g0336a0002c0002t0002g0004a0002c0002t0002g0005a0002c0002t0002g0024others(159): Show | HG00280.hp2 HG00438.hp1 HG00438.hp2 HG00544.hp2 HG00558.hp1 others(163): Show |
GWAS of allometric body-shape indices in UK Bioban others(109): Show |
186,825 British ancestry men/ | AAGAB | AAGAB | rs7173826-G | - | MODERATE | chr15 | T | G |
|
chr15:67249841
|
c.73+4718G>C | Smoking initiation0.00959 | a0001a0002 | a0001c0001a0002c0002 | a0001c0001t0006a0001c0001t0020a0002c0002t0001a0002c0002t0003a0002c0002t0007others(1): Show | a0001c0001t0006g0236a0001c0001t0006g0237a0001c0001t0006g0238a0001c0001t0020g0023a0002c0002t0001g0151others(106): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(108): Show |
Genetic diversity fuels gene discovery for tobacco others(17): Show |
3,382,012 European ancestry, East Asian ancestry, others(57): Show |
AAGAB | rs4776350-G | - | MODIFIER | chr15 | C | G | |
|
chr15:67250011
|
c.73+4548A>T | Smoking initiation0.00959 | a0001a0002 | a0001c0001a0002c0002 | a0001c0001t0006a0001c0001t0020a0002c0002t0001a0002c0002t0003a0002c0002t0007others(1): Show | a0001c0001t0006g0236a0001c0001t0006g0237a0001c0001t0006g0238a0001c0001t0020g0023a0002c0002t0001g0151others(106): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(108): Show |
Genetic diversity fuels gene discovery for tobacco others(17): Show |
3,382,012 European ancestry, East Asian ancestry, others(57): Show |
AAGAB | rs4776909-A | - | MODIFIER | chr15 | T | A | |
|
chr15:67253554
|
c.73+1005C>T | Smoking initiation0.00961 | a0001a0002 | a0001c0001a0002c0002 | a0001c0001t0006a0001c0001t0020a0002c0002t0001a0002c0002t0003a0002c0002t0007others(1): Show | a0001c0001t0006g0236a0001c0001t0006g0237a0001c0001t0006g0238a0001c0001t0020g0023a0002c0002t0001g0151others(106): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(108): Show |
Genetic diversity fuels gene discovery for tobacco others(17): Show |
3,382,012 European ancestry, East Asian ancestry, others(57): Show |
AAGAB | rs58074225-A | - | MODIFIER | chr15 | G | A | |
|
chr15:67254963
|
c.-332G>T |
Risk-taking behavior (multivariate analysis)< others(4): Show |
a0001a0002 | a0001c0001a0002c0002 | a0001c0001t0020a0001c0001t0021a0002c0002t0001a0002c0002t0003a0002c0002t0007others(1): Show | a0001c0001t0020g0023a0001c0001t0021g0025a0002c0002t0001g0151a0002c0002t0003g0007a0002c0002t0003g0008others(104): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(106): Show |
The Genetic and Neural Substrates of Externalizing others(10): Show |
1,506,537 European ancestry individuals/ | IQCH, AAGAB | rs3743347-? | - | MODIFIER | chr15 | C | A | |
|
chr15:67207139
|
c.715+1423T>G | Serum albumin levels0.0157 | a0001a0002 | a0001c0001a0002c0002 | a0001c0001t0006a0001c0001t0020a0002c0002t0001a0002c0002t0002a0002c0002t0003others(2): Show | a0001c0001t0006g0236a0001c0001t0006g0237a0001c0001t0006g0238a0001c0001t0020g0023a0002c0002t0001g0151others(112): Show | HG00280.hp2 HG00438.hp2 HG00544.hp2 HG00558.hp1 HG00609.hp2 others(115): Show |
A cross-population atlas of genetic associations f others(24): Show |
315,268 European ancestry individuals, 120,539 Eas others(29): Show |
AAGAB | rs11071940-C | - | MODIFIER | chr15 | A | C |
