Pfam Domain Viewer — HERC1 HERC1_chr15_63603618_63838948

Per-haplotype Pfam domain annotations from JoGo haplotype-resolved proteome

Gene Information
GeneHERC1
NCBI Gene IDGeneID:8925
HGNCHGNC:4867
RefSeq ProteinNP_003913.3
Protein Length4861 aa
Haplotypes20
Distinct Architectures2
Ref (a0001) ArchitectureWD40_RLD(368-560)->RCC1(373-418)->RCC1(421-472)->Alsin_RLD(455-580)->RCC1_2(458-488)->RCC1(476-526)->RCC1_2(513-541)->RCC1(529-576)->WD40_RLD(563-745)->RCC1_2(566-592)->RCC1(583-629)->Alsin_RLD(583-640)->RCC1_2(616-643)->RCC1(633-680)->RCC1_2(667-696)->RCC1(683-733)->SPRY(2074-2187)->Beta-prop_CAF1B_HIR1(3391-3533)->WD40_CDC20-Fz(3415-3461)->Beta-prop_WDR3_1st(3418-3461)->Beta-prop_TEP1_2nd(3418-3462)->WD40_WDHD1_1st(3421-3599)->Beta-prop_WDR5(3422-3461)->WD40(3423-3456)->Beta-prop_WDR35_TULP_N(3423-3462)->Beta-prop_THOC3(3427-3665)->WD40_CDC20-Fz(3486-3713)->Beta-prop_WDR5(3488-3667)->Beta-prop_IFT122_1st(3491-3653)->WD40_Prp19(3546-3791)->Beta-prop_WDR3_1st(3576-3716)->Beta-prop_IFT122_1st(3583-3655)->Beta-prop_WDR3_2nd(3584-3653)->Beta-prop_CAF1B_HIR1(3688-3819)->Beta-prop_IFT122_1st(3736-3807)->Beta-prop_WDR5(3737-3787)->Beta-prop_WDR3_1st(3738-3799)->Beta-prop_THOC3(3738-3804)->WD40(3738-3775)->WD40_WDHD1_1st(3739-3787)->WD40_RLD(3999-4357)->RCC1(3999-4042)->RCC1(4045-4097)->RCC1_2(4087-4112)->RCC1(4100-4149)->Alsin_RLD(4102-4207)->RCC1_2(4136-4164)->RCC1(4152-4201)->RCC1_2(4190-4217)->RCC1(4208-4254)->RCC1_2(4241-4265)->RCC1(4257-4306)->RCC1_2(4293-4322)->RCC1(4309-4358)->HECT(4560-4839)
Domain Architecture Diagram
Domain Differences vs Reference (a0001)
Haplotype ▲▼ Diff Type ▲▼ Pfam Acc ▲▼ Domain Name ▲▼ Ref Coords ▲▼ Alt Coords ▲▼ Ref Score ▲▼ Alt Score ▲▼
Haplotype Domain Details
Summary Statistics