Pfam Domain Viewer — LRP6 LRP6_chr12_12111025_12272044

Per-haplotype Pfam domain annotations from JoGo haplotype-resolved proteome

Gene Information
GeneLRP6
NCBI Gene IDGeneID:4040
HGNCHGNC:6698
RefSeq ProteinNP_002327.2
Protein Length1613 aa
Haplotypes10
Distinct Architectures3
Ref (a0001) ArchitectureLdl_recept_b(63-104)->Vgb_lyase(97-247)->DUF5050(105-267)->Ldl_recept_b(108-147)->Ldl_recept_b(150-191)->Ldl_recept_b(194-233)->EGF_LRP2(283-325)->FXa_inhibition(286-323)->cEGF(306-325)->Vgb_lyase(370-562)->Ldl_recept_b(372-412)->Ldl_recept_b(416-455)->DUF5050(417-574)->Ldl_recept_b(458-499)->SGL(476-525)->Ldl_recept_b(502-531)->EGF_LRP2(589-628)->FXa_inhibition(592-627)->Vgb_lyase(642-789)->Ldl_recept_b(674-714)->DUF5050(716-884)->Ldl_recept_b(718-757)->Ldl_recept_b(760-800)->Ldl_recept_b(803-839)->Ldl_recept_b(843-874)->FXa_inhibition(893-929)->EGF_LRP2(893-931)->DUF5050(1021-1182)->Ldl_recept_b(1069-1110)->Ldl_recept_b(1114-1153)->FXa_inhibition(1207-1243)->Ldl_recept_a(1248-1285)->Ldl_recept_a(1288-1322)->Ldl_recept_a(1326-1360)
Domain Architecture Diagram
Domain Differences vs Reference (a0001)
Haplotype ▲▼ Diff Type ▲▼ Pfam Acc ▲▼ Domain Name ▲▼ Ref Coords ▲▼ Alt Coords ▲▼ Ref Score ▲▼ Alt Score ▲▼
Haplotype Domain Details
Summary Statistics