Pfam Domain Viewer — LRRK2 LRRK2_chr12_40219997_40374285

Per-haplotype Pfam domain annotations from JoGo haplotype-resolved proteome

Gene Information ▼
GeneLRRK2
NCBI Gene IDGeneID:120892
EnsemblENSG00000188906.17
HGNCHGNC:18618
RefSeq ProteinNP_940980.4
Protein Length2527 aa
Haplotypes33
Distinct Architectures4
Ref (a0001) ArchitectureARM_LRRK2(17-649)->ANK_LRRK2(679-808)->LRR_8(1012-1070)->LRR_4(1012-1051)->LRR_8(1082-1119)->LRR_4(1108-1146)->LRR_8(1173-1208)->LRR_4(1173-1211)->LRR_8(1246-1300)->LRR_4(1246-1279)->LRR_14(1250-1300)->Roc(1336-1455)->Ras(1336-1461)->COR-A(1545-1671)->COR-B(1689-1858)->Pkinase(1884-2129)->PK_Tyr_Ser-Thr(1885-2129)->Beta-prop_LRRK2(2139-2496)->Beta-prop_RSE1_2nd(2175-2303)
Domain Architecture Diagram ▼
Domain Differences vs Reference (a0001) ▼
Haplotype ▲▼ Diff Type ▲▼ Pfam Acc ▲▼ Domain Name ▲▼ Ref Coords ▲▼ Alt Coords ▲▼ Ref Score ▲▼ Alt Score ▲▼
Haplotype Domain Details ▼
Summary Statistics ▼