Pfam Domain Viewer — TOPBP1 TOPBP1_chr3_133595238_133666941

Per-haplotype Pfam domain annotations from JoGo haplotype-resolved proteome

Gene Information
GeneTOPBP1
NCBI Gene IDGeneID:11073
HGNCHGNC:17008
RefSeq ProteinNP_008958.2
Protein Length1522 aa
Haplotypes13
Distinct Architectures1
Ref (a0001) ArchitectureTopBP1_BRCT0(9-104)->ECT2_BRCT0(56-102)->BRCT(105-175)->RTT107_BRCT_5(107-187)->PTCB-BRCT(109-171)->BRCT(196-271)->BRCT_2(198-278)->LIG3_BRCT(199-273)->PTCB-BRCT(204-266)->BRCT(355-431)->LIG3_BRCT(357-433)->BRCT_2(358-442)->PTCB-BRCT(363-403)->BRCT(549-620)->BRCT_2(552-627)->BRCT(643-723)->PTCB-BRCT(650-720)->BRCT(902-977)->PTCB-BRCT(908-973)->BRCT(1262-1337)->RTT107_BRCT_5(1287-1349)->BRCT_TopB1_SLF1(1391-1477)
Domain Architecture Diagram
Domain Differences vs Reference (a0001)
Haplotype ▲▼ Diff Type ▲▼ Pfam Acc ▲▼ Domain Name ▲▼ Ref Coords ▲▼ Alt Coords ▲▼ Ref Score ▲▼ Alt Score ▲▼
Haplotype Domain Details
Summary Statistics